GenomicAlignments

Representation and manipulation of short genomic alignments


Bioconductor version: Release (3.19)

Provides efficient containers for storing and manipulating short genomic alignments (typically obtained by aligning short reads to a reference genome). This includes read counting, computing the coverage, junction detection, and working with the nucleotide content of the alignments.

Author: Hervé Pagès [aut, cre], Valerie Obenchain [aut], Martin Morgan [aut], Fedor Bezrukov [ctb], Robert Castelo [ctb], Halimat C. Atanda [ctb] (Translated 'WorkingWithAlignedNucleotides' vignette from Sweave to RMarkdown / HTML.)

Maintainer: Hervé Pagès <hpages.on.github at gmail.com>

Citation (from within R, enter citation("GenomicAlignments")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GenomicAlignments")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("GenomicAlignments")
An Introduction to the GenomicAlignments Package PDF R Script
Counting reads with summarizeOverlaps PDF R Script
Overlap encodings PDF R Script
Working with aligned nucleotides (WORK-IN-PROGRESS!) HTML R Script
Reference Manual PDF
NEWS Text
Video
Video

Details

biocViews Alignment, Coverage, DataImport, Genetics, ImmunoOncology, Infrastructure, RNASeq, SNP, Sequencing, Software
Version 1.40.0
In Bioconductor since BioC 2.14 (R-3.1) (10.5 years)
License Artistic-2.0
Depends R (>= 4.0.0), methods, BiocGenerics(>= 0.37.0), S4Vectors(>= 0.27.12), IRanges(>= 2.23.9), GenomeInfoDb(>= 1.13.1), GenomicRanges(>= 1.55.3), SummarizedExperiment(>= 1.9.13), Biostrings(>= 2.55.7), Rsamtools(>= 1.31.2)
Imports methods, utils, stats, BiocGenerics, S4Vectors, IRanges, GenomicRanges, Biostrings, Rsamtools, BiocParallel
System Requirements
URL https://bioconductor.org/packages/GenomicAlignments
Bug Reports https://github.com/Bioconductor/GenomicAlignments/issues
See More
Suggests ShortRead, rtracklayer, BSgenome, GenomicFeatures, RNAseqData.HNRNPC.bam.chr14, pasillaBamSubset, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Dmelanogaster.UCSC.dm3.ensGene, BSgenome.Dmelanogaster.UCSC.dm3, BSgenome.Hsapiens.UCSC.hg19, DESeq2, edgeR, RUnit, knitr, BiocStyle
Linking To S4Vectors, IRanges
Enhances
Depends On Me AllelicImbalance, Basic4Cseq, ChIPexoQual, HelloRanges, ORFik, RiboDiPA, ShortRead, SplicingGraphs, groHMM, hiReadsProcessor, igvR, prebs, recoup, sequencing
Imports Me APAlyzer, ASpli, ATACseqQC, ATACseqTFEA, AneuFinder, BaalChIP, CAGEfightR, CAGEr, CNEr, CSSQ, ChIPQC, ChIPpeakAnno, CoverageView, CrispRVariants, DAMEfinder, DEScan2, DNAfusion, DegNorm, DiffBind, FLAMES, FRASER, GUIDEseq, GenomicFiles, GenomicPlot, GreyListChIP, Gviz, HTSeqGenie, IMAS, INSPEcT, IntEREst, MADSEQ, MDTS, Motif2Site, NADfinder, PICS, RNAmodR, Repitools, RiboProfiling, Rqc, SGSeq, SPLINTER, TAPseq, TCseq, UMI4Cats, Ularcirc, VaSP, VplotR, ZygosityPredictor, atena, bambu, biovizBase, breakpointR, cfDNAPro, chimeraviz, chromstaR, consensusDE, customProDB, derfinder, easyRNASeq, esATAC, gDNAx, gcapc, genomation, ggbio, gmapR, gmoviz, icetea, metagene2, metaseqR2, methylPipe, mosaics, msgbsR, plyranges, pram, proActiv, raer, ramwas, ribosomeProfilingQC, roar, rtracklayer, saseR, scPipe, scruff, seqsetvis, soGGi, spiky, srnadiff, strandCheckR, trackViewer, transcriptR, leeBamViews, alakazam, iimi, MAAPER, PACVr, VALERIE
Suggests Me BindingSiteFinder, BiocParallel, DEXSeq, ExperimentHub, GenomeInfoDb, GenomicDataCommons, GenomicFeatures, GenomicRanges, GenomicTuples, IRanges, QuasR, Rsamtools, SARC, Streamer, amplican, csaw, gage, igvShiny, similaRpeak, systemPipeR, NanoporeRNASeq, parathyroidSE, RNAseqData.HNRNPC.bam.chr14, seqmagick
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package GenomicAlignments_1.40.0.tar.gz
Windows Binary (x86_64) GenomicAlignments_1.40.0.zip
macOS Binary (x86_64) GenomicAlignments_1.40.0.tgz
macOS Binary (arm64) GenomicAlignments_1.40.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/GenomicAlignments
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/GenomicAlignments
Bioc Package Browser https://code.bioconductor.org/browse/GenomicAlignments/
Package Short Url https://bioconductor.org/packages/GenomicAlignments/
Package Downloads Report Download Stats