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Modeling RNA synthesis, processing and degradation with RNA-seq data

Bioconductor version: Release (3.19)

INSPEcT (INference of Synthesis, Processing and dEgradation rates from Transcriptomic data) RNA-seq data in time-course experiments or steady-state conditions, with or without the support of nascent RNA data.

Author: Stefano de Pretis

Maintainer: Stefano de Pretis <ste.depo at>, Mattia Furlan <Mattia.Furlan at>

Citation (from within R, enter citation("INSPEcT")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

INSPEcT - INference of Synthesis, Processing and dEgradation rates from Transcriptomic data HTML R Script
INSPEcT_GUI.html HTML R Script
Reference Manual PDF


biocViews GeneRegulation, RNASeq, Sequencing, Software, SystemsBiology, TimeCourse
Version 1.34.0
In Bioconductor since BioC 3.2 (R-3.2) (9 years)
License GPL-2
Depends R (>= 3.6), methods, Biobase, BiocParallel
Imports pROC, deSolve, rootSolve, KernSmooth, readxl, GenomicFeatures, GenomicRanges, IRanges, BiocGenerics, GenomicAlignments, Rsamtools, S4Vectors, GenomeInfoDb, DESeq2, plgem, rtracklayer, SummarizedExperiment, TxDb.Mmusculus.UCSC.mm9.knownGene, shiny
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Follow Installation instructions to use this package in your R session.

Source Package INSPEcT_1.34.0.tar.gz
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macOS Binary (x86_64) INSPEcT_1.34.0.tgz
macOS Binary (arm64) INSPEcT_1.34.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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