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BindingSiteFinder

This is the released version of BindingSiteFinder; for the devel version, see BindingSiteFinder.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14

Binding site defintion based on iCLIP data


Bioconductor version: Release (3.23)

Precise knowledge on the binding sites of an RNA-binding protein (RBP) is key to understand (post-) transcriptional regulatory processes. Here we present a workflow that describes how exact binding sites can be defined from iCLIP data. The package provides functions for binding site definition and result visualization. For details please see the vignette.

Author: Mirko Brüggemann [aut, cre] ORCID iD ORCID: 0000-0002-1778-0248 , Melina Klostermann [aut] ORCID iD ORCID: 0000-0003-3122-1095 , Kathi Zarnack [aut] ORCID iD ORCID: 0000-0003-3527-3378

Maintainer: Mirko Brüggemann <mirko.brueggemann at mail.de>

Citation (from within R, enter citation("BindingSiteFinder")):

Mirko Brüggemann, Melina Klostermann, Kathi Zarnack. BindingSiteFinder: Binding site defintion based on iCLIP data. doi:10.18129/B9.bioc.BindingSiteFinder, R package version 2.10.0, https://bioconductor.org/packages/BindingSiteFinder.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("BindingSiteFinder")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BindingSiteFinder")
Definition of binding sites from iCLIP signal HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Coverage, DataImport, FunctionalGenomics, GeneExpression, GeneRegulation, Sequencing, Software
Version2.10.0
In Bioconductor sinceBioC 3.14 (R-4.1) (5 years)
License Artistic-2.0
Depends GenomicRanges, R (>= 4.2)
Imports tidyr, tibble, plyr, matrixStats, stats, ggplot2, methods, rtracklayer, S4Vectors, ggforce, GenomeInfoDb, ComplexHeatmap, RColorBrewer, lifecycle, rlang, forcats, dplyr, GenomicFeatures, IRanges, kableExtra, ggdist
System Requirements
URL
Bug Reportshttps://github.com/ZarnackGroup/BindingSiteFinder/issues
See More
Suggests testthat, BiocStyle, knitr, rmarkdown, GenomicAlignments, scales, Gviz, xlsx, GGally, patchwork, viridis, ggplotify, SummarizedExperiment, DESeq2, ggpointdensity, ggrastr, ashr, txdbmaker, ggrepel, stringr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BindingSiteFinder_2.10.0.tar.gz
Windows Binary (x86_64) BindingSiteFinder_2.10.0.zip
macOS Binary (big-sur-x86_64) BindingSiteFinder_2.10.0.tgz
macOS Binary (sonoma-arm64) BindingSiteFinder_2.10.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/BindingSiteFinder
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/BindingSiteFinder
Package Short Url https://bioconductor.org/packages/BindingSiteFinder/
Package Downloads ReportDownload Stats