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crupR

This is the released version of crupR; for the devel version, see crupR.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21

An R package to predict condition-specific enhancers from ChIP-seq data


Bioconductor version: Release (3.23)

An R package that offers a workflow to predict condition-specific enhancers from ChIP-seq data. The prediction of regulatory units is done in four main steps: Step 1 - the normalization of the ChIP-seq counts. Step 2 - the prediction of active enhancers binwise on the whole genome. Step 3 - the condition-specific clustering of the putative active enhancers. Step 4 - the detection of possible target genes of the condition-specific clusters using RNA-seq counts.

Author: Persia Akbari Omgba [cre], Verena Laupert [aut], Martin Vingron [aut]

Maintainer: Persia Akbari Omgba <omgba at molgen.mpg.de>

Citation (from within R, enter citation("crupR")):

Verena Laupert, Martin Vingron. crupR: An R package to predict condition-specific enhancers from ChIP-seq data. doi:10.18129/B9.bioc.crupR, R package version 1.4.0, https://bioconductor.org/packages/crupR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("crupR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("crupR")
crupR Vignette HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DifferentialPeakCalling, FunctionalPrediction, GeneTarget, HistoneModification, PeakDetection, Software
Version1.4.0
In Bioconductor sinceBioC 3.21 (R-4.5) (1.5 years)
License GPL-3
Depends R (>= 4.4.0)
Imports bamsignals, Rsamtools, GenomicRanges, preprocessCore, randomForest, rtracklayer, Seqinfo, S4Vectors, ggplot2, matrixStats, dplyr, IRanges, GenomicAlignments, GenomicFeatures, TxDb.Mmusculus.UCSC.mm10.knownGene, TxDb.Mmusculus.UCSC.mm9.knownGene, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, reshape2, magrittr, stats, utils, grDevices, SummarizedExperiment, BiocParallel, fs, methods
System Requirements
URLhttps://github.com/akbariomgba/crupR
Bug Reportshttps://github.com/akbariomgba/crupR/issues
See More
Suggests GenomeInfoDb, testthat, BiocStyle, knitr, rmarkdown
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package crupR_1.4.0.tar.gz
Windows Binary (x86_64) crupR_1.3.0.zip
macOS Binary (big-sur-x86_64) crupR_1.4.0.tgz
macOS Binary (sonoma-arm64) crupR_1.3.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/crupR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/crupR
Package Short Url https://bioconductor.org/packages/crupR/
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