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MotifPeeker

This is the released version of MotifPeeker; for the devel version, see MotifPeeker.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21

Benchmarking Epigenomic Profiling Methods Using Motif Enrichment


Bioconductor version: Release (3.23)

MotifPeeker is used to compare and analyse datasets from epigenomic profiling methods with motif enrichment as the key benchmark. The package outputs an HTML report consisting of three sections: (1. General Metrics) Overview of peaks-related general metrics for the datasets (FRiP scores, peak widths and motif-summit distances). (2. Known Motif Enrichment Analysis) Statistics for the frequency of user-provided motifs enriched in the datasets. (3. Motif Discovery Enrichment Analysis) Statistics for the frequency of ab-initio discovered motifs enriched in the datasets and compared with known motifs.

Author: Hiranyamaya Dash [cre, aut] ORCID iD ORCID: 0009-0005-5514-505X , Thomas Roberts [aut] ORCID iD ORCID: 0009-0006-6244-8670 , Maria Weinert [aut] ORCID iD ORCID: 0000-0001-6187-1000 , Nathan Skene [aut] ORCID iD ORCID: 0000-0002-6807-3180

Maintainer: Hiranyamaya Dash <hdash.work at gmail.com>

Citation (from within R, enter citation("MotifPeeker")):

Hiranyamaya Dash, Thomas Roberts, Maria Weinert, Nathan Skene. MotifPeeker: Benchmarking Epigenomic Profiling Methods Using Motif Enrichment. doi:10.18129/B9.bioc.MotifPeeker, R package version 1.4.0, https://bioconductor.org/packages/MotifPeeker.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MotifPeeker")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MotifPeeker")
MotifPeeker HTML R Script
troubleshooting HTML R Script
Reference ManualPDF
NEWSText
INSTALLText

Details

biocViews Alignment, ChIPSeq, Epigenetics, FunctionalGenomics, Genetics, MotifDiscovery, MultipleComparison, QualityControl, SequenceMatching, Software
Version1.4.0
In Bioconductor sinceBioC 3.21 (R-4.5) (1.5 years)
License GPL (>= 3)
Depends R (>= 4.5.0)
Imports BiocFileCache, BiocParallel, DT, ggplot2, plotly, universalmotif, GenomicRanges, IRanges, rtracklayer, tools, htmltools, rmarkdown, viridis, SummarizedExperiment, htmlwidgets, Rsamtools, GenomicAlignments, Seqinfo, Biostrings, BSgenome, memes, S4Vectors, dplyr, purrr, tidyr, heatmaply, stats, utils
System RequirementsMEME Suite (v5.3.3 or above) <http://meme-suite.org/doc/download.html>
URLhttps://github.com/neurogenomics/MotifPeeker
Bug Reportshttps://github.com/neurogenomics/MotifPeeker/issues
See More
Suggests BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, BSgenome.Mmusculus.UCSC.mm39, downloadthis, knitr, markdown, methods, remotes, rworkflows, testthat (>= 3.0.0), withr, emoji, curl, jsonlite
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MotifPeeker_1.4.0.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) MotifPeeker_1.4.0.tgz
macOS Binary (sonoma-arm64) MotifPeeker_1.4.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/MotifPeeker
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MotifPeeker
Package Short Url https://bioconductor.org/packages/MotifPeeker/
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