DOI: 10.18129/B9.bioc.EpiCompare  

Comparison, Benchmarking & QC of Epigenomic Datasets

Bioconductor version: Release (3.18)

EpiCompare is used to compare and analyse epigenetic datasets for quality control and benchmarking purposes. The package outputs an HTML report consisting of three sections: (1. General metrics) Metrics on peaks (percentage of blacklisted and non-standard peaks, and peak widths) and fragments (duplication rate) of samples, (2. Peak overlap) Percentage and statistical significance of overlapping and non-overlapping peaks. Also includes upset plot and (3. Functional annotation) functional annotation (ChromHMM, ChIPseeker and enrichment analysis) of peaks. Also includes peak enrichment around TSS.

Author: Sera Choi [aut] , Brian Schilder [aut] , Leyla Abbasova [aut], Alan Murphy [aut] , Nathan Skene [aut] , Thomas Roberts [cre]

Maintainer: Thomas Roberts <tomroberts.work15 at gmail.com>

Citation (from within R, enter citation("EpiCompare")):


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biocViews ATACSeq, ChIPSeq, DNaseSeq, Epigenetics, FunctionalGenomics, Genetics, MultipleComparison, QualityControl, Software
Version 1.6.1
In Bioconductor since BioC 3.15 (R-4.2) (1.5 years)
License GPL-3
Depends R (>= 4.2.0)
Imports AnnotationHub, BRGenomics, ChIPseeker, data.table, genomation, GenomicRanges, IRanges, GenomeInfoDb, ggplot2, htmltools, methods, plotly, reshape2, rmarkdown, rtracklayer, stats, stringr, utils, BiocGenerics, downloadthis, parallel
Suggests rworkflows, BiocFileCache, BiocParallel, BiocStyle, clusterProfiler, GenomicAlignments, grDevices, htmlwidgets, knitr, org.Hs.eg.db, testthat (>= 3.0.0), tidyr, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, TxDb.Mmusculus.UCSC.mm9.knownGene, TxDb.Mmusculus.UCSC.mm10.knownGene, BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm9, BSgenome.Mmusculus.UCSC.mm10, ComplexUpset, plyranges, scales, Matrix, consensusSeekeR, heatmaply, viridis
URL https://github.com/neurogenomics/EpiCompare
BugReports https://github.com/neurogenomics/EpiCompare/issues
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macOS Binary (x86_64) EpiCompare_1.6.1.tgz
macOS Binary (arm64) EpiCompare_1.6.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/EpiCompare
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/EpiCompare
Bioc Package Browser https://code.bioconductor.org/browse/EpiCompare/
Package Short Url https://bioconductor.org/packages/EpiCompare/
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