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podkat

Position-Dependent Kernel Association Test

Bioconductor version: 3.23 · Package version: 1.44.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

This package provides an association test that is capable of dealing with very rare and even private variants. This is accomplished by a kernel-based approach that takes the positions of the variants into account. The test can be used for pre-processed matrix data, but also directly for variant data stored in VCF files. Association testing can be performed whole-genome, whole-exome, or restricted to pre-defined regions of interest. The test is complemented by tools for analyzing and visualizing the results.

DOI: 10.18129/B9.bioc.podkat

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("podkat")

Details

MaintainerUlrich Bodenhofer <ulrich@bodenhofer.com>
AuthorUlrich Bodenhofer [aut, cre]
LicenseGPL (>= 2)
URLhttps://github.com/UBod/podkat
System RequirementsGNU make
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsAnnotation, DataImport, Genetics, Sequencing, Software, VariantAnnotation, WholeGenome
Package Short Url https://bioconductor.org/packages/podkat/

Citation

From within R, enter citation("podkat"):

Ulrich Bodenhofer. podkat: Position-Dependent Kernel Association Test. doi:10.18129/B9.bioc.podkat, R package version 1.44.0, https://bioconductor.org/packages/podkat.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagepodkat_1.44.0.tar.gz
Windows binary (x86_64)podkat_1.44.0.zip
macOS binary (arm64)podkat_1.44.0.tgz
macOS binary (x86_64)podkat_1.44.0.tgz
Dependencies

Depends: R (>= 3.5.0), methods, Rsamtools (>= 1.99.1), GenomicRanges

Imports: Rcpp (>= 0.11.1), parallel, stats (>= 4.3.0), graphics, grDevices, utils, Biobase, BiocGenerics, Matrix, Seqinfo, IRanges, Biostrings, BSgenome (>= 1.32.0)

LinkingTo: Rcpp, Rhtslib (>= 1.15.3)

Suggests: BSgenome.Hsapiens.UCSC.hg38.masked, TxDb.Hsapiens.UCSC.hg38.knownGene, BSgenome.Mmusculus.UCSC.mm10.masked, GWASTools (>= 1.13.24), VariantAnnotation, SummarizedExperiment, knitr