DOI: 10.18129/B9.bioc.DSS    

Dispersion shrinkage for sequencing data

Bioconductor version: Release (3.7)

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Author: Hao Wu <hao.wu at emory.edu>

Maintainer: Hao Wu <hao.wu at emory.edu>

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PDF R Script Differential expression for RNA-seq data with dispersion shrinkage
PDF   Reference Manual
Text   NEWS


biocViews ChIPSeq, DNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, RNASeq, Sequencing, Software
Version 2.28.0
In Bioconductor since BioC 2.11 (R-2.15) (6 years)
License GPL
Depends R (>= 3.3), Biobase, bsseq, splines, methods
Imports stats, graphics, DelayedArray
Suggests BiocStyle
Depends On Me DMRcate
Imports Me kissDE
Suggests Me PROPER
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Source Package DSS_2.28.0.tar.gz
Windows Binary DSS_2.28.0.zip (32- & 64-bit)
Mac OS X 10.11 (El Capitan) DSS_2.28.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/DSS
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DSS
Package Short Url http://bioconductor.org/packages/DSS/
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