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nnSVG

This is the development version of nnSVG; for the stable release version, see nnSVG.

All Bioconductor versions of nnSVG

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15

Scalable identification of spatially variable genes in spatially-resolved transcriptomics data

Bioconductor version: 3.24 · Package version: 1.17.1

Method for scalable identification of spatially variable genes (SVGs) in spatially-resolved transcriptomics data. The method is based on nearest-neighbor Gaussian processes and uses the BRISC algorithm for model fitting and parameter estimation. Allows identification and ranking of SVGs with flexible length scales across a tissue slide or within spatial domains defined by covariates. Scales linearly with the number of spatial locations and can be applied to datasets containing thousands or more spatial locations.

Author: Lukas M. Weber [aut, cre] ORCID iD ORCID: 0000-0002-3282-1730 , Stephanie C. Hicks [aut] ORCID iD ORCID: 0000-0002-7858-0231

Maintainer: Lukas M. Weber <weberlm3 at gmail.com>

DOI: 10.18129/B9.bioc.nnSVG

Citation

From within R, enter citation("nnSVG"):

Lukas M. Weber, Stephanie C. Hicks. nnSVG: Scalable identification of spatially variable genes in spatially-resolved transcriptomics data. doi:10.18129/B9.bioc.nnSVG, R package version 1.17.1, https://bioconductor.org/packages/nnSVG.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("nnSVG")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.17.1
LicenseMIT + file LICENSE
URLhttps://github.com/lmweber/nnSVG
Bug Reportshttps://github.com/lmweber/nnSVG/issues
Last updated2026-07-14
In Bioconductor sinceBioC 3.15 (R-4.2) (4 years)
Downloads rank992 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsGeneExpression, Preprocessing, SingleCell, Software, Spatial, Transcriptomics
Package Short Url https://bioconductor.org/packages/nnSVG/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("nnSVG")
nnSVG Tutorial HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagennSVG_1.17.1.tar.gz
Windows binary (x86_64)nnSVG_1.17.1.zip
macOS binary (arm64)nnSVG_1.17.1.tgz
macOS binary (x86_64)nnSVG_1.17.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/nnSVG
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/nnSVG
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.2)

Imports: SpatialExperiment, SingleCellExperiment, SummarizedExperiment, BRISC, BiocParallel, Matrix, matrixStats, stats, methods

Suggests: BiocStyle, knitr, rmarkdown, STexampleData, WeberDivechaLCdata, scran, ggplot2, testthat

Reverse dependencies

Imports Me (1): spoon

Suggests Me (2): SEraster, tpSVG