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linkSet

This is the development version of linkSet; to use it, please install the devel version of Bioconductor.

Base Classes for Storing Genomic Link Data


Bioconductor version: Development (3.22)

Provides a comprehensive framework for representing, analyzing, and visualizing genomic interactions, particularly focusing on gene-enhancer relationships. The package extends the GenomicRanges infrastructure to handle paired genomic regions with specialized methods for chromatin interaction data from Hi-C, Promoter Capture Hi-C (PCHi-C), and single-cell ATAC-seq experiments. Key features include conversion from common interaction formats, annotation of promoters and enhancers, distance-based analyses, interaction strength metrics, statistical modeling using CHiCANE methodology, and tailored visualization tools. The package aims to standardize the representation of genomic interaction data while providing domain-specific functions not available in general genomic interaction packages.

Author: Gilbert Han [aut, cre] ORCID iD ORCID: 0009-0000-0293-2467

Maintainer: Gilbert Han <GilbertHan1011 at gmail.com>

Citation (from within R, enter citation("linkSet")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("linkSet")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("linkSet")
Hi-C Workflow with linkSet HTML R Script
linkSet: Base Classes for Storing Genomic Link Data HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Coverage, DataRepresentation, HiC, Sequencing, SingleCell, Software
Version 0.99.19
In Bioconductor since BioC 3.22 (R-4.5)
License MIT + file LICENSE
Depends GenomicRanges, S4Vectors, R (>= 4.5.0)
Imports methods, IRanges, GenomeInfoDb, BiocGenerics, Organism.dplyr, InteractionSet, ggplot2, patchwork, scales, foreach, iterators, stats, rlang, MASS, data.table, DBI, doParallel, AnnotationDbi
System Requirements
URL https://github.com/GilbertHan1011/linkSet https://gilberthan1011.github.io/linkSet
Bug Reports https://github.com/GilbertHan1011/linkSet/issues/new
See More
Suggests knitr, rmarkdown, testthat, TxDb.Mmusculus.UCSC.mm10.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, TxDb.Hsapiens.UCSC.hg19.knownGene, org.Mm.eg.db, org.Hs.eg.db, GenomicFeatures, GenomicInteractions, gamlss, gamlss.tr, BiocStyle, rtracklayer
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package linkSet_0.99.19.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/linkSet
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/linkSet
Bioc Package Browser https://code.bioconductor.org/browse/linkSet/
Package Short Url https://bioconductor.org/packages/linkSet/
Package Downloads Report Download Stats