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HIBAG

This is the released version of HIBAG; for the devel version, see HIBAG.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1

HLA Genotype Imputation with Attribute Bagging


Bioconductor version: Release (3.23)

Imputes HLA classical alleles using GWAS SNP data, and it relies on a training set of HLA and SNP genotypes. HIBAG can be used by researchers with published parameter estimates instead of requiring access to large training sample datasets. It combines the concepts of attribute bagging, an ensemble classifier method, with haplotype inference for SNPs and HLA types. Attribute bagging is a technique which improves the accuracy and stability of classifier ensembles using bootstrap aggregating and random variable selection.

Author: Xiuwen Zheng [aut, cre, cph] ORCID iD ORCID: 0000-0002-1390-0708 , Bruce Weir [ctb, ths] ORCID iD ORCID: 0000-0002-4883-1247

Maintainer: Xiuwen Zheng <zhengx at u.washington.edu>

Citation (from within R, enter citation("HIBAG")):

Xiuwen Zheng. HIBAG: HLA Genotype Imputation with Attribute Bagging. doi:10.18129/B9.bioc.HIBAG, R package version 1.48.2, https://bioconductor.org/packages/HIBAG.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HIBAG")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HIBAG")
HIBAG vignette html HTML R Script
HLA association vignette html HTML R Script
HIBAG algorithm implementation HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Genetics, Software, StatisticalMethod
Version1.48.2
In Bioconductor sinceBioC 3.1 (R-3.2) (11.5 years)
License GPL-3
Depends R (>= 3.2.0)
Imports methods, RcppParallel
System RequirementsGNU make
URLhttps://github.com/zhengxwen/HIBAG https://hibag.s3.amazonaws.com/index.html
See More
Suggests parallel, ggplot2, reshape2, gdsfmt, SNPRelate, SeqArray (>= 1.20.0), knitr, markdown, rmarkdown, Rsamtools
Linking To RcppParallel (>= 5.0.0)
Enhances
Depends On Me
Imports Me
Suggests Me PONG2
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HIBAG_1.48.2.tar.gz
Windows Binary (x86_64) HIBAG_1.48.2.zip
macOS Binary (big-sur-x86_64) HIBAG_1.48.2.tgz
macOS Binary (sonoma-arm64) HIBAG_1.48.2.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HIBAG
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HIBAG
Package Short Url https://bioconductor.org/packages/HIBAG/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.23Source Archive