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EMTscoreData

This is the released version of EMTscoreData; for the devel version, see EMTscoreData.

Single-cell RNA-seq datasets of EMT responses from Cook et al. (2020)


Bioconductor version: Release (3.23)

Provides 12 single-cell RNA-seq datasets profiling epithelial–mesenchymal transition (EMT) in human cancer cell lines (MCF7, OVCA420, DU145, and A549) under TGF-beta stimulation, kinase inhibition, and time-course conditions, as reported by Cook DP and Vanderhyden BC (2020). The datasets are distributed via ExperimentHub as SingleCellExperiment objects.

Author: Haimei Wen [aut, cre] ORCID iD ORCID: 0009-0006-1600-1210 , Tian Hong [fnd]

Maintainer: Haimei Wen <hudie.luoluo at gmail.com>

Citation (from within R, enter citation("EMTscoreData")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("EMTscoreData")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("EMTscoreData")
EMTscoreData Vignette HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews CancerData, ExperimentData, ExperimentHub, ExpressionData, RNASeqData, SingleCellData
Version 1.0.0
License GPL-3
Depends
Imports SummarizedExperiment, Seurat, SingleCellExperiment, AnnotationHub, ExperimentHub, ggplot2
System Requirements
URL https://github.com/wenmm/EMTscoreData
Bug Reports https://github.com/wenmm/EMTscoreData/issues
See More
Suggests BiocFileCache, SeuratObject, knitr, rmarkdown, googledrive, BiocStyle, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package EMTscoreData_1.0.0.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/EMTscoreData
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/EMTscoreData
Package Short Url https://bioconductor.org/packages/EMTscoreData/
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