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DuckDBGRanges

This is the development version of DuckDBGRanges; to use it, please install the devel version of Bioconductor.

DuckDB-Backed GenomicRanges Implementation


Bioconductor version: Development (3.24)

Provides DuckDB-backed implementations of GenomicRanges data structures for efficient, out-of-memory operations on large genomic interval datasets. The package includes DuckDBGRanges and DuckDBGRangesList classes with optimized range operations including restrict, flank, shift, findOverlaps, and distance calculations. Ideal for variant analysis, scATAC-seq peak analysis, and other genomic workflows requiring memory-efficient range operations on large datasets.

Author: Patrick Aboyoun [aut, cre], Genentech, Inc. [cph]

Maintainer: Patrick Aboyoun <aboyounp at gene.com>

Citation (from within R, enter citation("DuckDBGRanges")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("DuckDBGRanges")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DuckDBGRanges")
1. Introduction to DuckDBGRanges HTML R Script
2. Benchmarking DuckDBGRanges HTML R Script
3. Design and extension of DuckDBGRanges HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews DataImport, DataRepresentation, Infrastructure, Sequencing, Software
Version 0.99.4
In Bioconductor since BioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.6.0), methods, stats, DuckDBDataFrame, GenomicRanges
Imports bit64, BiocGenerics, S4Vectors, IRanges, Seqinfo, DelayedArray, DBI, dplyr, dbplyr
System Requirements
URL https://github.com/Genentech/DuckDBGRanges
Bug Reports https://github.com/Genentech/DuckDBGRanges/issues
See More
Suggests knitr, rmarkdown, BiocStyle, testthat, microbenchmark, arrow, TxDb.Hsapiens.UCSC.hg38.knownGene
Linking To
Enhances
Depends On Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DuckDBGRanges_0.99.4.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) DuckDBGRanges_0.99.4.tgz
macOS Binary (sonoma-arm64) DuckDBGRanges_0.99.4.tgz
Source Repository git clone https://git.bioconductor.org/packages/DuckDBGRanges
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DuckDBGRanges
Bioc Package Browser https://code.bioconductor.org/browse/DuckDBGRanges/
Package Short Url https://bioconductor.org/packages/DuckDBGRanges/
Package Downloads Report Download Stats