topGO
This is the released version of topGO; for the devel version, see topGO.
All Bioconductor versions of topGO
3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14, 2.13, 2.12, 2.11, 2.10, 2.9, 2.8, 2.7, 2.6, 2.5
Enrichment Analysis for Gene Ontology
Bioconductor version: 3.23 · Package version: 2.64.0
topGO package provides tools for testing GO terms while accounting for the topology of the GO graph. Different test statistics and different methods for eliminating local similarities and dependencies between GO terms can be implemented and applied.
Author: Adrian Alexa [aut], Jörg Rahnenführer [aut], Federico Marini [cre] 
Maintainer: Federico Marini <marinif at uni-mainz.de>
Citation
From within R, enter citation("topGO"):
Adrian Alexa, Jörg Rahnenführer. topGO: Enrichment Analysis for Gene Ontology. doi:10.18129/B9.bioc.topGO, R package version 2.64.0, https://bioconductor.org/packages/topGO.
Generated from the package metadata; it may differ from the package's own citation.
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("topGO")For older versions of R, please refer to the appropriate Bioconductor release.
Details
| Version | 2.64.0 |
| License | LGPL |
| URL | https://github.com/federicomarini/topGO |
| Bug Reports | https://github.com/federicomarini/topGO/issues |
| Last updated | 2026-04-28 |
| In Bioconductor since | BioC 2.5 or earlier (R-2.10) (16 years) |
| Downloads rank | 164 of 2,418 |
| Source branch | RELEASE_3_23 |
| Build report | Bioconductor build system, r-universe |
| biocViews | Annotation, GO, GeneExpression, GeneSetEnrichment, Microarray, Pathways, Sequencing, Software, SystemsBiology, Transcriptomics, Visualization |
| Package Short Url | https://bioconductor.org/packages/topGO/ |
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("topGO")| Gene set enrichment analysis with topGO | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Download
Follow the installation instructions to use this package in your R session.
| Source package | topGO_2.64.0.tar.gz |
| Windows binary (x86_64) | topGO_2.64.0.zip |
| macOS binary (arm64) | topGO_2.64.0.tgz |
| macOS binary (x86_64) | topGO_2.64.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/topGO |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/topGO |
| Package Downloads Report | Download Stats |
Dependencies
Depends: R (>= 2.10.0), methods, BiocGenerics (>= 0.13.6), graph (>= 1.14.0), Biobase (>= 2.0.0), GO.db (>= 2.3.0), AnnotationDbi (>= 1.7.19), SparseM (>= 0.73)
Imports: lattice, matrixStats, DBI
Suggests: ALL, hgu95av2.db, hgu133a.db, genefilter, multtest, Rgraphviz, globaltest, knitr, BiocStyle, rmarkdown
Reverse dependencies
Depends On Me (5): BgeeDB, compEpiTools, EGSEA, ideal, tRanslatome
Imports Me (10): APL, cellity, consICA, ExpHunterSuite, GRaNIE, mosdef, OmaDB, pcaExplorer, transcriptogramer, ViSEAGO
Suggests Me (8): DeeDeeExperiment, diffwrap, fenr, FGNet, GeDi, geva, IntramiRExploreR, miRNAtap