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An R package for the easy provision of simple but complete tab-delimited genomic annotation from a variety of sources and organisms

Bioconductor version: Release (3.19)

Provides an interface to build a unified database of genomic annotations and their coordinates (gene, transcript and exon levels). It is aimed to be used when simple tab-delimited annotations (or simple GRanges objects) are required instead of the more complex annotation Bioconductor packages. Also useful when combinatorial annotation elements are reuired, such as RefSeq coordinates with Ensembl biotypes. Finally, it can download, construct and handle annotations with versioned genes and transcripts (where available, e.g. RefSeq and latest Ensembl). This is particularly useful in precision medicine applications where the latter must be reported.

Author: Panagiotis Moulos [aut, cre]

Maintainer: Panagiotis Moulos <moulos at>

Citation (from within R, enter citation("sitadela")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Building a simple annotation database HTML R Script
Reference Manual PDF


biocViews AlternativeSplicing, BiomedicalInformatics, ChIPSeq, DataImport, FunctionalGenomics, RNASeq, Sequencing, Software, SystemsBiology, Transcription, Transcriptomics, WorkflowStep
Version 1.12.0
In Bioconductor since BioC 3.13 (R-4.1) (3 years)
License Artistic-2.0
Depends R (>= 4.1.0)
Imports Biobase, BiocGenerics, biomaRt, Biostrings, GenomeInfoDb, GenomicFeatures, GenomicRanges, IRanges, methods, parallel, Rsamtools, RSQLite, rtracklayer, S4Vectors, tools, txdbmaker, utils
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Suggests BiocStyle, BSgenome, knitr, rmarkdown, RMySQL, RUnit
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Follow Installation instructions to use this package in your R session.

Source Package sitadela_1.12.0.tar.gz
Windows Binary (64-bit only)
macOS Binary (x86_64) sitadela_1.12.0.tgz
macOS Binary (arm64) sitadela_1.12.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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