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Simplify Functional Enrichment Results

Bioconductor version: Release (3.18)

A new clustering algorithm, "binary cut", for clustering similarity matrices of functional terms is implemeted in this package. It also provides functions for visualizing, summarizing and comparing the clusterings.

Author: Zuguang Gu [aut, cre]

Maintainer: Zuguang Gu <z.gu at dkfz.de>

Citation (from within R, enter citation("simplifyEnrichment")):


To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

A Shiny app to interactively visualize clustering results HTML R Script
Simplify Functional Enrichment Results HTML R Script
Word Cloud Annotation HTML R Script
Reference Manual PDF


biocViews Clustering, GO, GeneSetEnrichment, Software, Visualization
Version 1.12.0
In Bioconductor since BioC 3.12 (R-4.0) (3.5 years)
License MIT + file LICENSE
Depends R (>= 3.6.0), BiocGenerics, grid
Imports GOSemSim, ComplexHeatmap(>= 2.7.4), circlize, GetoptLong, digest, tm, GO.db, org.Hs.eg.db, AnnotationDbi, slam, methods, clue, grDevices, graphics, stats, utils, proxyC, Matrix, cluster (>= 1.14.2), colorspace, GlobalOptions (>= 0.1.0)
System Requirements
URL https://github.com/jokergoo/simplifyEnrichment https://simplifyEnrichment.github.io
See More
Suggests knitr, ggplot2, cowplot, mclust, apcluster, MCL, dbscan, igraph, gridExtra, dynamicTreeCut, testthat, gridGraphics, clusterProfiler, msigdbr, DOSE, DO.db, reactome.db, flexclust, BiocManager, InteractiveComplexHeatmap(>= 0.99.11), shiny, shinydashboard, cola, hu6800.db, rmarkdown, genefilter, gridtext, fpc
Linking To
Depends On Me
Imports Me
Suggests Me cola, InteractiveComplexHeatmap, pareg, simona
Links To Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package simplifyEnrichment_1.12.0.tar.gz
Windows Binary simplifyEnrichment_1.12.0.zip
macOS Binary (x86_64) simplifyEnrichment_1.12.0.tgz
macOS Binary (arm64) simplifyEnrichment_1.12.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/simplifyEnrichment
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/simplifyEnrichment
Bioc Package Browser https://code.bioconductor.org/browse/simplifyEnrichment/
Package Short Url https://bioconductor.org/packages/simplifyEnrichment/
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