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Generate synthetic nucleosome maps

Bioconductor version: Release (3.19)

This package can generate a synthetic map with reads covering the nucleosome regions as well as a synthetic map with forward and reverse reads emulating next-generation sequencing. The synthetic hybridization data of “Tiling Arrays” can also be generated. The user has choice between three different distributions for the read positioning: Normal, Student and Uniform. In addition, a visualization tool is provided to explore the synthetic nucleosome maps.

Author: Rawane Samb [aut], Astrid Deschênes [cre, aut] , Pascal Belleau [aut] , Arnaud Droit [aut]

Maintainer: Astrid Deschênes <adeschen at>

Citation (from within R, enter citation("nucleoSim")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Generate synthetic nucleosome maps HTML R Script
Reference Manual PDF


biocViews Alignment, Genetics, Sequencing, Software, StatisticalMethod
Version 1.32.0
In Bioconductor since BioC 3.3 (R-3.3) (8 years)
License Artistic-2.0
Imports stats, IRanges, S4Vectors, graphics, methods
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Suggests BiocStyle, BiocGenerics, knitr, rmarkdown, testthat
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Depends On Me
Imports Me
Suggests Me RJMCMCNucleosomes
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Follow Installation instructions to use this package in your R session.

Source Package nucleoSim_1.32.0.tar.gz
Windows Binary (64-bit only)
macOS Binary (x86_64) nucleoSim_1.32.0.tgz
macOS Binary (arm64) nucleoSim_1.32.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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