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XDE: a Bayesian hierarchical model for cross-study analysis of differential gene expression

Bioconductor version: Release (3.19)

Multi-level model for cross-study detection of differential gene expression.

Author: R.B. Scharpf, G. Parmigiani, A.B. Nobel, and H. Tjelmeland

Maintainer: Robert Scharpf <rscharpf at>

Citation (from within R, enter citation("XDE")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

XDE Vignette PDF R Script
XdeParameterClass Vignette PDF R Script
Reference Manual PDF


biocViews DifferentialExpression, Microarray, Software
Version 2.50.0
In Bioconductor since BioC 2.2 (R-2.7) (16 years)
License LGPL-2
Depends R (>= 2.10.0), Biobase(>= 2.5.5)
Imports BiocGenerics, genefilter, graphics, grDevices, gtools, methods, stats, utils, mvtnorm, RColorBrewer, GeneMeta, siggenes
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Follow Installation instructions to use this package in your R session.

Source Package XDE_2.50.0.tar.gz
Windows Binary (64-bit only)
macOS Binary (x86_64) XDE_2.50.0.tgz
macOS Binary (arm64) XDE_2.50.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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