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SynMut: Designing Synonymously Mutated Sequences with Different Genomic Signatures

Bioconductor version: Release (3.19)

There are increasing demands on designing virus mutants with specific dinucleotide or codon composition. This tool can take both dinucleotide preference and/or codon usage bias into account while designing mutants. It is a powerful tool for in silico designs of DNA sequence mutants.

Author: Haogao Gu [aut, cre], Leo L.M. Poon [led]

Maintainer: Haogao Gu <hggu at>

Citation (from within R, enter citation("SynMut")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

SynMut: Designing Synonymous Mutants for DNA Sequences HTML R Script
Reference Manual PDF


biocViews ExperimentalDesign, Preprocessing, SequenceMatching, Software
Version 1.20.0
In Bioconductor since BioC 3.9 (R-3.6) (5 years)
License GPL-2
Imports seqinr, methods, Biostrings, stringr, BiocGenerics
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Suggests BiocManager, knitr, rmarkdown, testthat, devtools, prettydoc, glue
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Follow Installation instructions to use this package in your R session.

Source Package SynMut_1.20.0.tar.gz
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macOS Binary (x86_64) SynMut_1.20.0.tgz
macOS Binary (arm64) SynMut_1.20.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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