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Summix

Summix2: A suite of methods to estimate, adjust, and leverage substructure in genetic summary data

Bioconductor version: 3.23 · Package version: 2.18.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

This package contains the Summix2 method for estimating and adjusting for substructure in genetic summary allele frequency data. The function summix() estimates reference group proportions using a mixture model. The adjAF() function produces adjusted allele frequencies for an observed group with reference group proportions matching a target individual or sample. The summix_local() function estimates local ancestry mixture proportions and performs selection scans in genetic summary data.

DOI: 10.18129/B9.bioc.Summix

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Summix")

Details

MaintainerAudrey Hendricks <audrey.hendricks@cuanschutz.edu>
AuthorAudrey Hendricks [cre], Price Adelle [aut], Stoneman Haley [aut]
LicenseMIT + file LICENSE
Bug Reportshttps://github.com/Bioconductor/Summix/issues
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsGenetics, Software, StatisticalMethod, WholeGenome
Package Short Url https://bioconductor.org/packages/Summix/

Citation

From within R, enter citation("Summix"):

Price Adelle, Stoneman Haley. Summix: Summix2: A suite of methods to estimate, adjust, and leverage substructure in genetic summary data. doi:10.18129/B9.bioc.Summix, R package version 2.18.0, https://bioconductor.org/packages/Summix.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageSummix_2.18.0.tar.gz
Windows binary (x86_64)Summix_2.18.0.zip
macOS binary (arm64)Summix_2.18.0.tgz
macOS binary (x86_64)Summix_2.18.0.tgz
Dependencies

Depends: R (>= 4.3)

Imports: dplyr, nloptr, magrittr, methods, tibble, tidyselect, BEDASSLE, scales, visNetwork, randomcoloR

Suggests: rmarkdown, markdown, knitr, testthat (>= 3.0.0)