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This is the development version of Summix; for the stable release version, see Summix.

Summix2: A method to estimate and adjust for substructure in genetic summary data

Bioconductor version: Development (3.19)

This package contains the Summix2 method for estimating and adjusting for substructure in genetic summary allele frequency data. The function summix() estimates reference group proportions using a mixture model. The adjAF() function produces adjusted allele frequencies for an observed group with reference group proportions matching a target individual or sample. The summix_local() function estimates local ancestry mixture proportions and performs selection scans in genetic summary data.

Author: Audrey Hendricks [cre], Price Adelle [aut], Stoneman Haley [aut]

Maintainer: Audrey Hendricks <audrey.hendricks at cuanschutz.edu>

Citation (from within R, enter citation("Summix")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Summix.html HTML R Script
Reference Manual PDF


biocViews Genetics, Software, StatisticalMethod, WholeGenome
Version 2.9.1
In Bioconductor since BioC 3.13 (R-4.1) (3 years)
License MIT + file LICENSE
Depends R (>= 4.3)
Imports dplyr, nloptr, magrittr, methods, tibble, tidyselect
System Requirements
Bug Reports https://github.com/Bioconductor/Summix/issues
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Suggests rmarkdown, markdown, knitr, testthat (>= 3.0.0)
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Follow Installation instructions to use this package in your R session.

Source Package Summix_2.9.1.tar.gz
Windows Binary Summix_2.9.1.zip
macOS Binary (x86_64) Summix_2.9.1.tgz
macOS Binary (arm64) Summix_2.9.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/Summix
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/Summix
Bioc Package Browser https://code.bioconductor.org/browse/Summix/
Package Short Url https://bioconductor.org/packages/Summix/
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