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MIRit

Integrate microRNA and gene expression to decipher pathway complexity

Bioconductor version: 3.23 · Package version: 1.8.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

MIRit is an R package that provides several methods for investigating the relationships between miRNAs and genes in different biological conditions. In particular, MIRit allows to explore the functions of dysregulated miRNAs, and makes it possible to identify miRNA-gene regulatory axes that control biological pathways, thus enabling the users to unveil the complexity of miRNA biology. MIRit is an all-in-one framework that aims to help researchers in all the central aspects of an integrative miRNA-mRNA analyses, from differential expression analysis to network characterization.

DOI: 10.18129/B9.bioc.MIRit

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MIRit")

Details

MaintainerJacopo Ronchi <jacopo.ronchi@unimib.it>
AuthorJacopo Ronchi [aut, cre] (ORCID: <https://orcid.org/0000-0001-5520-4631>), Maria Foti [fnd] (ORCID: <https://orcid.org/0000-0002-4481-1900>)
LicenseGPL (>= 3)
URLhttps://jacopo-ronchi.github.io/MIRit/, https://github.com/jacopo-ronchi/MIRit
Bug Reportshttps://github.com/jacopo-ronchi/MIRit/issues
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsDifferentialExpression, Epigenetics, FunctionalGenomics, GeneExpression, GeneRegulation, Network, NetworkEnrichment, NetworkInference, Pathways, Software, SystemsBiology
Package Short Url https://bioconductor.org/packages/MIRit/

Citation

From within R, enter citation("MIRit"):

Jacopo Ronchi. MIRit: Integrate microRNA and gene expression to decipher pathway complexity. doi:10.18129/B9.bioc.MIRit, R package version 1.8.0, https://bioconductor.org/packages/MIRit.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageMIRit_1.8.0.tar.gz
macOS binary (arm64)MIRit_1.8.0.tgz
macOS binary (x86_64)MIRit_1.8.0.tgz
Dependencies

Depends: MultiAssayExperiment, R (>= 4.4.0)

Imports: AnnotationDbi, BiocFileCache, BiocParallel, DESeq2, edgeR, fgsea, genekitr, geneset, ggplot2, ggpubr, graph, graphics, graphite, grDevices, httr, limma, methods, Rcpp, Rgraphviz (>= 2.44.0), rlang, stats, utils

LinkingTo: Rcpp

Suggests: BiocStyle, biomaRt, BSgenome.Hsapiens.UCSC.hg38, GenomicRanges, ggrepel, ggridges, Gviz, gwasrapidd, knitr, MonoPoly, org.Hs.eg.db, rmarkdown, testthat (>= 3.0.0)