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A Functional Approach To Impute Genetically Regulated Expression

Bioconductor version: Release (3.19)

Impute a GReX (Genetically Regulated Expression) for a set of genes in a sample of individuals, using a method based on the Total Binding Affinity (TBA). Statistical models to impute GReX can be trained with a training dataset where the real total expression values are known.

Author: Alessandro Lussana [aut, cre]

Maintainer: Alessandro Lussana <alessandro.lussana at>

Citation (from within R, enter citation("AffiXcan")):


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biocViews DimensionReduction, GeneExpression, GeneRegulation, PrincipalComponent, Regression, Software, Transcription
Version 1.22.0
In Bioconductor since BioC 3.8 (R-3.5) (5.5 years)
License GPL-3
Depends R (>= 3.6), SummarizedExperiment
Imports MultiAssayExperiment, BiocParallel, crayon
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