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multipointR

This is the development version of multipointR; to use it, please install the devel version of Bioconductor.

A package to compare intensities of point patterns across samples with spatial parametric models


Bioconductor version: Development (3.24)

`multipointR` is a package to compare the distribution of cells in an image or cross images with point process models. On a single image level point process models (`ppm`) model the spatial distribution of a cell type point pattern as a function of spatial covariates while accounting for natural spacing of cells. The main model class considered in `multipointR` are inhomgoeneous Gibb's point process models. Across multiple images, users can either compare multiple univariate `ppm` models in a for loop or fit one joint model across all images with `mppm`. `multipointR` provides an interface between `SpatialExperiment` and `SpatialFeatureExperiment` objects and let's users flexibly define their own `ppm`/`mppm` models with R's formula interface.

Author: Martin Emons [aut, cre] ORCID iD ORCID: 0009-0000-5219-5311 , Wolfgang Huber [aut] ORCID iD ORCID: 0000-0002-0474-2218 , Mark D. Robinson [aut, fnd] ORCID iD ORCID: 0000-0002-3048-5518

Maintainer: Martin Emons <martin.emons at uzh.ch>

Citation (from within R, enter citation("multipointR")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("multipointR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("multipointR")
Introduction to `multipointR` HTML R Script
Reference Manual PDF

Details

biocViews SingleCell, Software, Spatial, Transcriptomics
Version 0.99.5
In Bioconductor since BioC 3.24 (R-4.6)
License GPL (>= 3)
Depends R (>= 4.1.0)
Imports SummarizedExperiment, methods, SpatialExperiment, spatstat.geom, spatstat.model, spatstat.explore, formula.tools, mgcv, dplyr, ggplot2, reformulas, S4Vectors, rlang
System Requirements
URL https://github.com/mjemons/multipointR
Bug Reports https://github.com/mjemons/multipointR/issues
See More
Suggests knitr, BiocStyle, patchwork, SpatialFeatureExperiment, rmarkdown, SpatialDatasets, sosta, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package multipointR_0.99.5.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) multipointR_0.99.5.tgz
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/multipointR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/multipointR
Bioc Package Browser https://code.bioconductor.org/browse/multipointR/
Package Short Url https://bioconductor.org/packages/multipointR/
Package Downloads Report Download Stats