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methylCC

This is the released version of methylCC; for the devel version, see methylCC.

Estimate the cell composition of whole blood in DNA methylation samples


Bioconductor version: Release (3.23)

A tool to estimate the cell composition of DNA methylation whole blood sample measured on any platform technology (microarray and sequencing).

Author: Stephanie C. Hicks [aut, cre] ORCID iD ORCID: 0000-0002-7858-0231 , Rafael Irizarry [aut] ORCID iD ORCID: 0000-0002-3944-4309

Maintainer: Stephanie C. Hicks <shicks19 at jhu.edu>

Citation (from within R, enter citation("methylCC")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methylCC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methylCC")
The methylCC user's guide HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews DNAMethylation, MethylSeq, MethylationArray, Microarray, Sequencing, Software, WholeGenome
Version 1.26.0
In Bioconductor since BioC 3.10 (R-3.6) (7 years)
License GPL-3
Depends R (>= 3.6), FlowSorted.Blood.450k
Imports Biobase, GenomicRanges, IRanges, S4Vectors, dplyr, magrittr, minfi, bsseq, quadprog, stats, utils, bumphunter, genefilter, methods, IlluminaHumanMethylation450kmanifest, IlluminaHumanMethylation450kanno.ilmn12.hg19
System Requirements
URL https://github.com/stephaniehicks/methylCC/
Bug Reports https://github.com/stephaniehicks/methylCC/
See More
Suggests rmarkdown, knitr, testthat (>= 2.1.0), BiocGenerics, BiocStyle, tidyr, ggplot2
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package methylCC_1.26.0.tar.gz
Windows Binary (x86_64) methylCC_1.26.0.zip
macOS Binary (big-sur-x86_64) methylCC_1.26.0.tgz
macOS Binary (sonoma-arm64) methylCC_1.26.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/methylCC
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/methylCC
Bioc Package Browser https://code.bioconductor.org/browse/methylCC/
Package Short Url https://bioconductor.org/packages/methylCC/
Package Downloads Report Download Stats