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mgcca

This is the development version of mgcca; to use it, please install the devel version of Bioconductor.

Generalized Canonical Correlation Analysis with Missing Individuals


Bioconductor version: Development (3.24)

Implements Generalized Canonical Correlation Analysis (GCCA) with missing individuals (whole missing rows; van de Velden and Bijmolt, 2006) for multi-block omics integration. The package operates directly on HDF5 matrices via the BigDataStatMeth C++ API to scale computations; R functions are thin wrappers around the C++ core.

Author: Dolors Pelegri-Siso [aut, cre] ORCID iD ORCID: 0000-0002-5993-3003 , Isaac Subirana [aut], Juan R. Gonzalez [aut] ORCID iD ORCID: 0000-0003-3267-2146

Maintainer: Dolors Pelegri-Siso <dolors.pelegri at isglobal.org>

Citation (from within R, enter citation("mgcca")):

Dolors Pelegri-Siso, Isaac Subirana, Juan R. Gonzalez. mgcca: Generalized Canonical Correlation Analysis with Missing Individuals. doi:10.18129/B9.bioc.mgcca, R package version 0.99.7, https://bioconductor.org/packages/mgcca.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("mgcca")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("mgcca")
Generalized Canonical Correlation with missing individuals - Examples HTML
How much of a shared subspace is carried by group structure? HTML
Reference ManualPDF
NEWSText

Details

biocViews DimensionReduction, Epigenetics, GeneExpression, Metabolomics, PrincipalComponent, Software, StatisticalMethod, Transcriptomics
Version0.99.7
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports BigDataStatMeth (>= 2.0.6), MASS, rlang (>= 1.1.0), withr, Rcpp (>= 1.0.6), ggplot2 (>= 3.4.0), ggthemes, impute, SummarizedExperiment, graphics, grDevices, grid, methods, stats, utils
System RequirementsGNU make, C++17
URLhttps://isglobal-brge.github.io/mgcca/ https://github.com/isglobal-brge/mgcca http://brge.isglobal.org
Bug Reportshttps://github.com/isglobal-brge/mgcca/issues
See More
Suggests BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0), MultiAssayExperiment, Biobase, wordcloud, GenomicRanges, IRanges, BiocGenerics, made4, RSpectra, GenomeInfoDb, curatedTCGAData, TCGAutils, TxDb.Hsapiens.UCSC.hg19.knownGene, org.Hs.eg.db
Linking To Rcpp, RcppEigen, Rhdf5lib, BigDataStatMeth, BH
Enhances
Depends On Me
Imports Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/mgcca
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/mgcca
Package Short Url https://bioconductor.org/packages/mgcca/
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