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tigre

This is the development version of tigre; for the stable release version, see tigre.

Transcription factor Inference through Gaussian process Reconstruction of Expression


Bioconductor version: Development (3.19)

The tigre package implements our methodology of Gaussian process differential equation models for analysis of gene expression time series from single input motif networks. The package can be used for inferring unobserved transcription factor (TF) protein concentrations from expression measurements of known target genes, or for ranking candidate targets of a TF.

Author: Antti Honkela, Pei Gao, Jonatan Ropponen, Miika-Petteri Matikainen, Magnus Rattray, Neil D. Lawrence

Maintainer: Antti Honkela <antti.honkela at helsinki.fi>

Citation (from within R, enter citation("tigre")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("tigre")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews Bayesian, GeneExpression, GeneRegulation, Microarray, NetworkInference, Software, TimeCourse, Transcription
Version 1.57.0
In Bioconductor since BioC 2.6 (R-2.11) (14 years)
License AGPL-3
Depends R (>= 2.11.0), BiocGenerics, Biobase
Imports methods, AnnotationDbi, gplots, graphics, grDevices, stats, utils, annotate, DBI, RSQLite
System Requirements
URL https://github.com/ahonkela/tigre
Bug Reports https://github.com/ahonkela/tigre/issues
See More
Suggests drosgenome1.db, puma, lumi, BiocStyle, BiocManager
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary
macOS Binary (x86_64) tigre_1.57.0.tgz
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/tigre
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/tigre
Bioc Package Browser https://code.bioconductor.org/browse/tigre/
Package Short Url https://bioconductor.org/packages/tigre/
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