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scDD

This is the development version of scDD; for the stable release version, see scDD.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5

Mixture modeling of single-cell RNA-seq data to identify genes with differential distributions


Bioconductor version: Development (3.24)

This package implements a method to analyze single-cell RNA- seq Data utilizing flexible Dirichlet Process mixture models. Genes with differential distributions of expression are classified into several interesting patterns of differences between two conditions. The package also includes functions for simulating data with these patterns from negative binomial distributions.

Author: Keegan Korthauer [cre, aut] ORCID iD ORCID: 0000-0002-4565-1654

Maintainer: Keegan Korthauer <keegan at stat.ubc.ca>

Citation (from within R, enter citation("scDD")):

Keegan Korthauer. scDD: Mixture modeling of single-cell RNA-seq data to identify genes with differential distributions. doi:10.18129/B9.bioc.scDD, R package version 1.37.0, https://bioconductor.org/packages/scDD.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("scDD")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("scDD")
scDD Quickstart PDF R Script
Reference ManualPDF
NEWSText

Details

biocViews Bayesian, Clustering, DifferentialExpression, ImmunoOncology, MultipleComparison, RNASeq, SingleCell, Software, Visualization
Version1.37.0
In Bioconductor sinceBioC 3.5 (R-3.4) (9.5 years)
License GPL-2
Depends R (>= 3.5.0)
Imports fields, mclust, BiocParallel, outliers, ggplot2, EBSeq, arm, SingleCellExperiment, SummarizedExperiment, grDevices, graphics, stats, S4Vectors, scran
System Requirements
URLhttps://github.com/kdkorthauer/scDD
Bug Reportshttps://github.com/kdkorthauer/scDD/issues
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package scDD_1.37.0.tar.gz
Windows Binary (x86_64) scDD_1.37.0.zip
macOS Binary (big-sur-x86_64) scDD_1.37.0.tgz
macOS Binary (sonoma-arm64) scDD_1.37.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/scDD
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/scDD
Package Short Url https://bioconductor.org/packages/scDD/
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