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markeR

This is the development version of markeR; for the stable release version, see markeR.

All versions 3.24 (devel), 3.23 (release), 3.22

An R Toolkit for Evaluating Gene Signatures as Phenotypic Markers


Bioconductor version: Development (3.24)

markeR is an R package that provides a modular and extensible framework for the systematic evaluation of gene sets as phenotypic markers using transcriptomic data. The package is designed to support both quantitative analyses and visual exploration of gene set behaviour across experimental and clinical phenotypes. It implements multiple methods, including score-based and enrichment approaches, and also allows the exploration of expression behaviour of individual genes. In addition, users can assess the similarity of their own gene sets against established collections (e.g., those from MSigDB), facilitating biological interpretation.

Author: Rita Martins-Silva [aut, cre] ORCID iD ORCID: 0000-0002-1067-7993 , Alexandre Kaizeler [aut, ctb] ORCID iD ORCID: 0000-0002-9117-6073 , Nuno Luís Barbosa-Morais [aut, led, ths] ORCID iD ORCID: 0000-0002-1215-0538

Maintainer: Rita Martins-Silva <rita.silva at gimm.pt>

Citation (from within R, enter citation("markeR")):

Rita Martins-Silva, Alexandre Kaizeler, Nuno Luís Barbosa-Morais. markeR: An R Toolkit for Evaluating Gene Signatures as Phenotypic Markers. doi:10.18129/B9.bioc.markeR, R package version 1.3.1, https://bioconductor.org/packages/markeR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("markeR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("markeR")
Introduction to markeR HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Classification, GeneExpression, GeneSetEnrichment, Software, Transcriptomics, Visualization
Version1.3.1
In Bioconductor sinceBioC 3.22 (R-4.5) (1 year)
License Artistic-2.0
Depends R (>= 4.5.0)
Imports circlize, edgeR, ComplexHeatmap, ggh4x, ggplot2, ggpubr, grid, gridExtra, pROC, RColorBrewer, reshape2, rstatix, scales, stats, utils, fgsea, limma, ggrepel, effectsize, msigdbr, tibble
System Requirements
URLhttps://diseasetranscriptomicslab.github.io/markeR/ https://github.com/DiseaseTranscriptomicsLab/markeR https://doi.org/10.1093/nargab/lqag057
Bug Reportshttps://github.com/DiseaseTranscriptomicsLab/markeR/issues
See More
Suggests devtools, markdown, renv, testthat, BiocManager, knitr, rmarkdown, roxygen2, mockery, covr, magick, BiocStyle
Linking To
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package markeR_1.3.1.tar.gz
Windows Binary (x86_64) markeR_1.3.1.zip (64-bit only)
macOS Binary (big-sur-x86_64) markeR_1.3.1.tgz
macOS Binary (sonoma-arm64) markeR_1.3.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/markeR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/markeR
Package Short Url https://bioconductor.org/packages/markeR/
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