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aggregateBioVar

This is the development version of aggregateBioVar; for the stable release version, see aggregateBioVar.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12

Differential Gene Expression Analysis for Multi-subject scRNA-seq


Bioconductor version: Development (3.24)

For single cell RNA-seq data collected from more than one subject (e.g. biological sample or technical replicates), this package contains tools to summarize single cell gene expression profiles at the level of subject. A SingleCellExperiment object is taken as input and converted to a list of SummarizedExperiment objects, where each list element corresponds to an assigned cell type. The SummarizedExperiment objects contain aggregate gene-by-subject count matrices and inter-subject column metadata for individual subjects that can be processed using downstream bulk RNA-seq tools.

Author: Jason Ratcliff [aut, cre] ORCID iD ORCID: 0000-0001-7079-334X , Andrew Thurman [aut], Michael Chimenti [ctb], Alejandro Pezzulo [ctb]

Maintainer: Jason Ratcliff <jason-ratcliff at uiowa.edu>

Citation (from within R, enter citation("aggregateBioVar")):

Jason Ratcliff, Andrew Thurman. aggregateBioVar: Differential Gene Expression Analysis for Multi-subject scRNA-seq. doi:10.18129/B9.bioc.aggregateBioVar, R package version 1.23.0, https://bioconductor.org/packages/aggregateBioVar.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("aggregateBioVar")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("aggregateBioVar")
Multi-subject scRNA-seq Analysis HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DifferentialExpression, GeneExpression, RNASeq, SingleCell, Software, Transcription, Transcriptomics
Version1.23.0
In Bioconductor sinceBioC 3.12 (R-4.0) (6 years)
License GPL-3
Depends R (>= 4.0)
Imports stats, methods, S4Vectors, SummarizedExperiment, SingleCellExperiment, Matrix, tibble, rlang
System Requirements
URLhttps://github.com/jasonratcliff/aggregateBioVar
Bug Reportshttps://github.com/jasonratcliff/aggregateBioVar/issues
See More
Suggests BiocStyle, magick, knitr, rmarkdown, testthat, BiocGenerics, DESeq2, magrittr, dplyr, ggplot2, cowplot, ggtext, RColorBrewer, pheatmap, viridis
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package aggregateBioVar_1.23.0.tar.gz
Windows Binary (x86_64) aggregateBioVar_1.23.0.zip
macOS Binary (big-sur-x86_64) aggregateBioVar_1.23.0.tgz
macOS Binary (sonoma-arm64) aggregateBioVar_1.23.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/aggregateBioVar
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/aggregateBioVar
Package Short Url https://bioconductor.org/packages/aggregateBioVar/
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