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XINA

This is the development version of XINA; for the stable release version, see XINA.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8

Multiplexes Isobaric Mass Tagged-based Kinetics Data for Network Analysis


Bioconductor version: Development (3.24)

The aim of XINA is to determine which proteins exhibit similar patterns within and across experimental conditions, since proteins with co-abundance patterns may have common molecular functions. XINA imports multiple datasets, tags dataset in silico, and combines the data for subsequent subgrouping into multiple clusters. The result is a single output depicting the variation across all conditions. XINA, not only extracts coabundance profiles within and across experiments, but also incorporates protein-protein interaction databases and integrative resources such as KEGG to infer interactors and molecular functions, respectively, and produces intuitive graphical outputs.

Author: Lang Ho Lee <lhlee at bwh.harvard.edu> and Sasha A. Singh <sasingh at bwh.harvard.edu>

Maintainer: Lang Ho Lee <lhlee at bwh.harvard.edu> and Sasha A. Singh <sasingh at bwh.harvard.edu>

Citation (from within R, enter citation("XINA")):

Lang Ho Lee and Sasha A. Singh. XINA: Multiplexes Isobaric Mass Tagged-based Kinetics Data for Network Analysis. doi:10.18129/B9.bioc.XINA, R package version 1.31.0, https://bioconductor.org/packages/XINA.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("XINA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("XINA")
xina_user_code HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Network, Proteomics, RNASeq, Software, SystemsBiology
Version1.31.0
In Bioconductor sinceBioC 3.8 (R-3.5) (8 years)
License GPL-3
Depends R (>= 3.5)
Imports mclust, plyr, alluvial, ggplot2, igraph, gridExtra, tools, grDevices, graphics, utils, STRINGdb
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package XINA_1.31.0.tar.gz
Windows Binary (x86_64) XINA_1.31.0.zip
macOS Binary (big-sur-x86_64) XINA_1.31.0.tgz
macOS Binary (sonoma-arm64) XINA_1.31.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/XINA
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/XINA
Package Short Url https://bioconductor.org/packages/XINA/
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