XINA

Multiplexes Isobaric Mass Tagged-based Kinetics Data for Network Analysis


Bioconductor version: Release (3.19)

The aim of XINA is to determine which proteins exhibit similar patterns within and across experimental conditions, since proteins with co-abundance patterns may have common molecular functions. XINA imports multiple datasets, tags dataset in silico, and combines the data for subsequent subgrouping into multiple clusters. The result is a single output depicting the variation across all conditions. XINA, not only extracts coabundance profiles within and across experiments, but also incorporates protein-protein interaction databases and integrative resources such as KEGG to infer interactors and molecular functions, respectively, and produces intuitive graphical outputs.

Author: Lang Ho Lee <lhlee at bwh.harvard.edu> and Sasha A. Singh <sasingh at bwh.harvard.edu>

Maintainer: Lang Ho Lee <lhlee at bwh.harvard.edu> and Sasha A. Singh <sasingh at bwh.harvard.edu>

Citation (from within R, enter citation("XINA")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("XINA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("XINA")
xina_user_code HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Network, Proteomics, RNASeq, Software, SystemsBiology
Version 1.22.0
In Bioconductor since BioC 3.8 (R-3.5) (6 years)
License GPL-3
Depends R (>= 3.5)
Imports mclust, plyr, alluvial, ggplot2, igraph, gridExtra, tools, grDevices, graphics, utils, STRINGdb
System Requirements
URL
See More
Suggests knitr, rmarkdown
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package XINA_1.22.0.tar.gz
Windows Binary XINA_1.22.0.zip (64-bit only)
macOS Binary (x86_64) XINA_1.22.0.tgz
macOS Binary (arm64) XINA_1.22.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/XINA
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/XINA
Bioc Package Browser https://code.bioconductor.org/browse/XINA/
Package Short Url https://bioconductor.org/packages/XINA/
Package Downloads Report Download Stats