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NormalyzerDE

This is the development version of NormalyzerDE; for the stable release version, see NormalyzerDE.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8

Evaluation of normalization methods and calculation of differential expression analysis statistics


Bioconductor version: Development (3.24)

NormalyzerDE provides screening of normalization methods for LC-MS based expression data. It calculates a range of normalized matrices using both existing approaches and a novel time-segmented approach, calculates performance measures and generates an evaluation report. Furthermore, it provides an easy utility for Limma- or ANOVA- based differential expression analysis.

Author: Jakob Willforss

Maintainer: Jakob Willforss <jakob.willforss at hotmail.com>

Citation (from within R, enter citation("NormalyzerDE")):

Jakob Willforss. NormalyzerDE: Evaluation of normalization methods and calculation of differential expression analysis statistics. doi:10.18129/B9.bioc.NormalyzerDE, R package version 1.31.0, https://bioconductor.org/packages/NormalyzerDE.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("NormalyzerDE")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("NormalyzerDE")
Differential expression and countering technical biases using NormalyzerDE HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Bayesian, DifferentialExpression, Metabolomics, MultipleComparison, Normalization, Proteomics, Software, Visualization
Version1.31.0
In Bioconductor sinceBioC 3.8 (R-3.5) (8 years)
License Artistic-2.0
Depends R (>= 4.1.0)
Imports vsn, preprocessCore, limma, MASS, ape, car, ggplot2, methods, utils, stats, SummarizedExperiment, matrixStats, ggforce
System Requirements
URLhttps://computationalproteomics.github.io/NormalyzerDE/ https://github.com/ComputationalProteomics/NormalyzerDE
See More
Suggests knitr, testthat, rmarkdown, roxygen2, hexbin, BiocStyle
Linking To
Enhances
Depends On Me
Imports Me PRONE
Suggests Me normScore
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package NormalyzerDE_1.31.0.tar.gz
Windows Binary (x86_64) NormalyzerDE_1.31.0.zip
macOS Binary (big-sur-x86_64) NormalyzerDE_1.31.0.tgz
macOS Binary (sonoma-arm64) NormalyzerDE_1.31.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/NormalyzerDE
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/NormalyzerDE
Package Short Url https://bioconductor.org/packages/NormalyzerDE/
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