This is the development version of HEM; for the stable release version, see HEM.

Heterogeneous error model for identification of differentially expressed genes under multiple conditions

Bioconductor version: Development (3.20)

This package fits heterogeneous error models for analysis of microarray data

Author: HyungJun Cho <hcho at virginia.edu> and Jae K. Lee <jaeklee at virginia.edu>

Maintainer: HyungJun Cho <hcho at virginia.edu>

Citation (from within R, enter citation("HEM")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

HEM Overview PDF
Reference Manual PDF


biocViews DifferentialExpression, Microarray, Software
Version 1.77.0
In Bioconductor since BioC 1.7 (R-2.2) (18.5 years)
License GPL (>= 2)
Depends R (>= 2.1.0)
Imports Biobase, grDevices, stats, utils
System Requirements
URL http://www.healthsystem.virginia.edu/internet/hes/biostat/bioinformatics/
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Follow Installation instructions to use this package in your R session.

Source Package HEM_1.77.0.tar.gz
Windows Binary HEM_1.77.0.zip
macOS Binary (x86_64) HEM_1.77.0.tgz
macOS Binary (arm64) HEM_1.77.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/HEM
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/HEM
Bioc Package Browser https://code.bioconductor.org/browse/HEM/
Package Short Url https://bioconductor.org/packages/HEM/
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