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TiDEomics

This is the development version of TiDEomics; to use it, please install the devel version of Bioconductor.

Time-course Differential Expression analysis of omics data


Bioconductor version: Development (3.24)

TiDEomics provides a comprehensive workflow for multi-group time-course omics data analysis, analysing time-dominant, group-dominant, and group-specific temporal effects through pairwise differential expression, variance decomposition, and co-expression module analysis (WGCNA). The package integrates quality control, data processing, functional enrichment, and extensive visualisation. It supports datasets with missing values (e.g., mass spectrometry-based proteomics), and operates on SummarizedExperiment objects to ensure compatibility with the Bioconductor ecosystem.

Author: Tianen He [aut, cre] ORCID iD ORCID: 0000-0001-6864-0723

Maintainer: Tianen He <tianen.he at ndm.ox.ac.uk>

Citation (from within R, enter citation("TiDEomics")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("TiDEomics")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TiDEomics")
TiDEomics Tutorial HTML R Script
Reference Manual PDF

Details

biocViews DifferentialExpression, GeneExpression, MassSpectrometry, MultipleComparison, Pathways, Proteomics, QualityControl, Software, TimeCourse, Transcriptomics, Visualization
Version 0.99.4
In Bioconductor since BioC 3.24 (R-4.6)
License GPL (>= 2)
Depends R (>= 4.6.0)
Imports circlize, clusterProfiler, ComplexHeatmap, dplyr, enrichplot, ggforce, ggh4x, ggplot2, ggplotify, ggpubr, ggrepel, ggridges, ggsci, limma, lme4, methods, patchwork, pbapply, PCAtools, randtests, scales, SummarizedExperiment, tibble, tidyr, Trendy, umap, WGCNA
System Requirements
URL https://github.com/hte123/TiDEomics https://hte123.github.io/TiDEomics
Bug Reports https://github.com/hte123/TiDEomics/issues
See More
Suggests knitr, rmarkdown, BiocStyle, testthat (>= 3.1.0), plotly, enrichR, org.Hs.eg.db, org.Mm.eg.db, msigdbr, DeeDeeExperiment
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package TiDEomics_0.99.4.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) TiDEomics_0.99.4.tgz
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/TiDEomics
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/TiDEomics
Bioc Package Browser https://code.bioconductor.org/browse/TiDEomics/
Package Short Url https://bioconductor.org/packages/TiDEomics/
Package Downloads Report Download Stats