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HiLDA

This is the released version of HiLDA; for the devel version, see HiLDA.

All Bioconductor versions of HiLDA

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10

Conducting statistical inference on comparing the mutational exposures of mutational signatures by using hierarchical latent Dirichlet allocation

Bioconductor version: 3.23 · Package version: 1.26.0

A package built under the Bayesian framework of applying hierarchical latent Dirichlet allocation. It statistically tests whether the mutational exposures of mutational signatures (Shiraishi-model signatures) are different between two groups. The package also provides inference and visualization.

Author: Zhi Yang [aut, cre], Yuichi Shiraishi [ctb]

Maintainer: Zhi Yang <zyang895 at gmail.com>

DOI: 10.18129/B9.bioc.HiLDA

Citation

From within R, enter citation("HiLDA"):

Zhi Yang. HiLDA: Conducting statistical inference on comparing the mutational exposures of mutational signatures by using hierarchical latent Dirichlet allocation. doi:10.18129/B9.bioc.HiLDA, R package version 1.26.0, https://bioconductor.org/packages/HiLDA.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HiLDA")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.26.0
LicenseGPL-3
URLhttps://github.com/USCbiostats/HiLDA https://doi.org/10.1101/577452
Bug Reportshttps://github.com/USCbiostats/HiLDA/issues
System RequirementsJAGS 4.0.0
Last updated2026-04-28
In Bioconductor sinceBioC 3.10 (R-3.6) (6 years)
Downloads rank1064 of 2,418
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsBayesian, Sequencing, Software, SomaticMutation, StatisticalMethod
Package Short Url https://bioconductor.org/packages/HiLDA/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiLDA")
HiLDA: a package for testing the burdens of mutational signatures HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packageHiLDA_1.26.0.tar.gz
Windows binary (x86_64)HiLDA_1.26.0.zip
macOS binary (arm64)HiLDA_1.26.0.tgz
macOS binary (x86_64)HiLDA_1.26.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HiLDA
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HiLDA
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.1), ggplot2

Imports: R2jags, abind, cowplot, grid, forcats, stringr, GenomicRanges, S4Vectors, XVector, Biostrings, GenomicFeatures, BSgenome.Hsapiens.UCSC.hg19, BiocGenerics, tidyr, grDevices, stats, TxDb.Hsapiens.UCSC.hg19.knownGene, utils, methods, Rcpp

LinkingTo: Rcpp

Suggests: knitr, rmarkdown, testthat, BiocStyle

Reverse dependencies

Imports Me (1): selectKSigs