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HPiP

This is the released version of HPiP; for the devel version, see HPiP.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14

Host-Pathogen Interaction Prediction


Bioconductor version: Release (3.23)

HPiP (Host-Pathogen Interaction Prediction) uses an ensemble learning algorithm for prediction of host-pathogen protein-protein interactions (HP-PPIs) using structural and physicochemical descriptors computed from amino acid-composition of host and pathogen proteins.The proposed package can effectively address data shortages and data unavailability for HP-PPI network reconstructions. Moreover, establishing computational frameworks in that regard will reveal mechanistic insights into infectious diseases and suggest potential HP-PPI targets, thus narrowing down the range of possible candidates for subsequent wet-lab experimental validations.

Author: Matineh Rahmatbakhsh [aut, trl, cre], Mohan Babu [led]

Maintainer: Matineh Rahmatbakhsh <matinerb.94 at gmail.com>

Citation (from within R, enter citation("HPiP")):

Matineh Rahmatbakhsh. HPiP: Host-Pathogen Interaction Prediction. doi:10.18129/B9.bioc.HPiP, R package version 1.18.0, https://bioconductor.org/packages/HPiP.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HPiP")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HPiP")
Introduction to HPiP HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews GenePrediction, Network, NetworkInference, Proteomics, Software, StructuralPrediction, SystemsBiology
Version1.18.0
In Bioconductor sinceBioC 3.14 (R-4.1) (5 years)
License MIT + file LICENSE
Depends R (>= 4.1)
Imports dplyr (>= 1.0.6), httr (>= 1.4.2), readr, tidyr, tibble, utils, stringr, magrittr, caret, corrplot, ggplot2, pROC, PRROC, igraph, graphics, stats, purrr, grDevices, protr, MCL
System Requirements
URLhttps://github.com/mrbakhsh/HPiP
Bug Reportshttps://github.com/mrbakhsh/HPiP/issues
See More
Suggests rmarkdown, colorspace, e1071, kernlab, ranger, SummarizedExperiment, Biostrings, randomForest, gprofiler2, gridExtra, ggthemes, BiocStyle, BiocGenerics, RUnit, tools, knitr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HPiP_1.18.0.tar.gz
Windows Binary (x86_64) HPiP_1.18.0.zip
macOS Binary (big-sur-x86_64) HPiP_1.18.0.tgz
macOS Binary (sonoma-arm64) HPiP_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HPiP
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HPiP
Package Short Url https://bioconductor.org/packages/HPiP/
Package Downloads ReportDownload Stats