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DAssemble

This is the development version of DAssemble; to use it, please install the devel version of Bioconductor.

Ensemble Models for Differential Analysis


Bioconductor version: Development (3.24)

The DAssemble package implements an ensemble framework for differential-abundance and differential-expression analysis across bulk RNA-seq, single-cell RNA-seq, and microbiome studies. It wraps a collection of popular DA/DE methods as core methods and combines them via Cauchy Combination Tests (CCT), optionally augmented by simple enhancers such as Wilcoxon, Kolmogorov–Smirnov, and presence–absence logistic regression.

Author: Ziyu Liu [aut], Nalin Arora [aut, cre] ORCID iD ORCID: 0009-0009-1340-688X , Chuxuan Gao [aut], Himel Mallick [aut]

Maintainer: Nalin Arora <naa4050 at med.cornell.edu>

Citation (from within R, enter citation("DAssemble")):

Ziyu Liu, Nalin Arora, Chuxuan Gao, Himel Mallick. DAssemble: Ensemble Models for Differential Analysis. doi:10.18129/B9.bioc.DAssemble, R package version 0.99.4, https://bioconductor.org/packages/DAssemble.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("DAssemble")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DAssemble")
DAssemble: Ensemble Differential Analysis HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews DifferentialExpression, Microbiome, Normalization, RNASeq, Regression, SingleCell, Software, StatisticalMethod
Version0.99.4
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports stats, utils, dplyr, MultiAssayExperiment, SummarizedExperiment
System Requirements
URLhttps://github.com/himelmallick/DAssemble
Bug Reportshttps://github.com/himelmallick/DAssemble/issues
See More
Suggests DESeq2, edgeR, limma, dearseq, metagenomeSeq, MAST, cplm, brglm2, dfadjust, glmmTMB, logging, MASS, pbapply, preprocessCore, Maaslin2, maaslin3, LOCOM2, MicrobiomeStat, ANCOMBC, ALDEx2, airway, scran, SingleCellExperiment, knitr, rmarkdown, BiocStyle, phyloseq, S4Vectors, testthat (>= 3.0.0), boot
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DAssemble_0.99.4.tar.gz
Windows Binary (x86_64) DAssemble_0.99.4.zip
macOS Binary (big-sur-x86_64) DAssemble_0.99.4.tgz
macOS Binary (sonoma-arm64) DAssemble_0.99.4.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/DAssemble
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/DAssemble
Package Short Url https://bioconductor.org/packages/DAssemble/
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