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BOBaFIT

This is the released version of BOBaFIT; for the devel version, see BOBaFIT.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15

Refitting diploid region profiles using a clustering procedure


Bioconductor version: Release (3.23)

This package provides a method to refit and correct the diploid region in copy number profiles. It uses a clustering algorithm to identify pathology-specific normal (diploid) chromosomes and then use their copy number signal to refit the whole profile. The package is composed by three functions: DRrefit (the main function), ComputeNormalChromosome and PlotCluster.

Author: Andrea Poletti [aut], Gaia Mazzocchetti [aut, cre], Vincenza Solli [aut]

Maintainer: Gaia Mazzocchetti <bioinformatic.seragnoli at gmail.com>

Citation (from within R, enter citation("BOBaFIT")):

Andrea Poletti, Gaia Mazzocchetti, Vincenza Solli. BOBaFIT: Refitting diploid region profiles using a clustering procedure. doi:10.18129/B9.bioc.BOBaFIT, R package version 1.16.0, https://bioconductor.org/packages/BOBaFIT.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("BOBaFIT")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BOBaFIT")
BOBaFIT.Rmd HTML R Script
Data preparation using TCGA-BRCA database.Rmd HTML R Script
Reference ManualPDF

Details

biocViews Clustering, CopyNumberVariation, Normalization, Software, Visualization
Version1.16.0
In Bioconductor sinceBioC 3.15 (R-4.2) (4.5 years)
License GPL (>= 3)
Depends R (>= 2.10)
Imports dplyr, NbClust, ggplot2, ggbio, grDevices, stats, tidyr, GenomicRanges, ggforce, stringr, plyranges, methods, utils, magrittr
System Requirements
URLhttps://github.com/andrea-poletti-unibo/BOBaFIT
Bug Reportshttps://github.com/andrea-poletti-unibo/BOBaFIT/issues
See More
Suggests rmarkdown, markdown, BiocStyle, knitr, testthat (>= 3.0.0), utils, testthat
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Depends On Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BOBaFIT_1.16.0.tar.gz
Windows Binary (x86_64) BOBaFIT_1.16.0.zip
macOS Binary (big-sur-x86_64) BOBaFIT_1.16.0.tgz
macOS Binary (sonoma-arm64) BOBaFIT_1.16.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/BOBaFIT
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/BOBaFIT
Package Short Url https://bioconductor.org/packages/BOBaFIT/
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