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chipseqDB

A Bioconductor Workflow to Detect Differential Binding in ChIP-seq Data

Bioconductor version: 3.23 · Package version: 1.36.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

Describes a computational workflow for performing a DB analysis with sliding windows. The aim is to facilitate the practical implementation of window-based DB analyses by providing detailed code and expected output. The workflow described here applies to any ChIP-seq experiment with multiple experimental conditions and multiple biological samples in one or more of the conditions. It detects and summarizes DB regions between conditions in a de novo manner, i.e., without making any prior assumptions about the location or width of bound regions. Detected regions are then annotated according to their proximity to genes.

DOI: 10.18129/B9.bioc.chipseqDB

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("chipseqDB")

Details

MaintainerAaron Lun <infinite.monkeys.with.keyboards@gmail.com>
AuthorAaron Lun [aut, cre], Gordon Smyth [aut]
LicenseArtistic-2.0
URLhttps://www.bioconductor.org/help/workflows/chipseqDB/
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsEpigeneticsWorkflow, ImmunoOncologyWorkflow, Workflow
Package Short Url https://bioconductor.org/packages/chipseqDB/

Citation

From within R, enter citation("chipseqDB"):

Aaron Lun, Gordon Smyth. chipseqDB: A Bioconductor Workflow to Detect Differential Binding in ChIP-seq Data. doi:10.18129/B9.bioc.chipseqDB, R package version 1.36.0, https://bioconductor.org/packages/chipseqDB.

Generated from the package metadata; it may differ from the package's own citation.

Download

Follow the installation instructions to use this package in your R session.

Source packagechipseqDB_1.36.0.tar.gz
Dependencies

Suggests: chipseqDBData, BiocStyle, BiocFileCache, ChIPpeakAnno, Gviz, Rsamtools, TxDb.Mmusculus.UCSC.mm10.knownGene, csaw, edgeR, knitr, org.Mm.eg.db, rtracklayer, rmarkdown