DOI: 10.18129/B9.bioc.synergyfinder    

Calculate and Visualize Synergy Scores for Drug Combinations

Bioconductor version: Release (3.12)

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix. Based on this package, we also provide a web application for users who prefer more friendly user interface.

Author: Liye He <liye.he at>, Jing Tang <jing.tang at>, Shuyu Zheng <shuyu.zheng at>

Maintainer: Shuyu Zheng <shuyu.zheng at>

Citation (from within R, enter citation("synergyfinder")):


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biocViews Software, StatisticalMethod
Version 2.4.7
In Bioconductor since BioC 3.4 (R-3.3) (4.5 years)
License Mozilla Public License 2.0
Depends R (>= 3.6.0), methods
Imports drc (>= 2.5-12), reshape2 (>= 1.4.1), ggplot2 (>= 2.1.0), grid (>= 3.2.4), lattice (>= 0.20-33), nleqslv (>= 3.0), stats (>= 3.3.0), graphics (>= 3.3.0), grDevices (>= 3.3.0)
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