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gemini

GEMINI: Variational inference approach to infer genetic interactions from pairwise CRISPR screens

Bioconductor version: 3.23 · Package version: 1.26.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

GEMINI uses log-fold changes to model sample-dependent and independent effects, and uses a variational Bayes approach to infer these effects. The inferred effects are used to score and identify genetic interactions, such as lethality and recovery. More details can be found in Zamanighomi et al. 2019 (in press).

DOI: 10.18129/B9.bioc.gemini

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("gemini")

Details

MaintainerSidharth Jain <sidharthsjain@gmail.com>
AuthorMahdi Zamanighomi [aut], Sidharth Jain [aut, cre]
LicenseBSD_3_clause + file LICENSE
Bug Reportshttps://github.com/sellerslab/gemini/issues
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsBayesian, CRISPR, DataImport, Software
Package Short Url https://bioconductor.org/packages/gemini/

Citation

From within R, enter citation("gemini"):

Mahdi Zamanighomi, Sidharth Jain. gemini: GEMINI: Variational inference approach to infer genetic interactions from pairwise CRISPR screens. doi:10.18129/B9.bioc.gemini, R package version 1.26.0, https://bioconductor.org/packages/gemini.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagegemini_1.26.0.tar.gz
Windows binary (x86_64)gemini_1.26.0.zip
macOS binary (arm64)gemini_1.26.0.tgz
macOS binary (x86_64)gemini_1.26.0.tgz
Dependencies

Depends: R (>= 4.1.0)

Imports: dplyr, grDevices, ggplot2, magrittr, mixtools, scales, pbmcapply, parallel, stats, utils

Suggests: knitr, rmarkdown, testthat