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RNAAgeCalc

This is the released version of RNAAgeCalc; for the devel version, see RNAAgeCalc.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11

A multi-tissue transcriptional age calculator


Bioconductor version: Release (3.23)

It has been shown that both DNA methylation and RNA transcription are linked to chronological age and age related diseases. Several estimators have been developed to predict human aging from DNA level and RNA level. Most of the human transcriptional age predictor are based on microarray data and limited to only a few tissues. To date, transcriptional studies on aging using RNASeq data from different human tissues is limited. The aim of this package is to provide a tool for across-tissue and tissue-specific transcriptional age calculation based on GTEx RNASeq data.

Author: Xu Ren [aut, cre], Pei Fen Kuan [aut]

Maintainer: Xu Ren <xuren2120 at gmail.com>

Citation (from within R, enter citation("RNAAgeCalc")):

Xu Ren, Pei Fen Kuan. RNAAgeCalc: A multi-tissue transcriptional age calculator. doi:10.18129/B9.bioc.RNAAgeCalc, R package version 1.24.0, https://bioconductor.org/packages/RNAAgeCalc.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("RNAAgeCalc")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RNAAgeCalc")
RNAAgeCalc HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews GeneExpression, RNASeq, Software
Version1.24.0
In Bioconductor sinceBioC 3.11 (R-4.0) (6.5 years)
License GPL-2
Depends R (>= 3.6)
Imports ggplot2, recount, impute, AnnotationDbi, org.Hs.eg.db, stats, SummarizedExperiment, methods
System Requirements
URLhttps://github.com/reese3928/RNAAgeCalc
Bug Reportshttps://github.com/reese3928/RNAAgeCalc/issues
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package RNAAgeCalc_1.24.0.tar.gz
Windows Binary (x86_64) RNAAgeCalc_1.24.0.zip
macOS Binary (big-sur-x86_64) RNAAgeCalc_1.24.0.tgz
macOS Binary (sonoma-arm64) RNAAgeCalc_1.24.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/RNAAgeCalc
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/RNAAgeCalc
Package Short Url https://bioconductor.org/packages/RNAAgeCalc/
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