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Analyze and correct probe positional bias in microarray data due to RNA degradation

Bioconductor version: Release (3.18)

The package helps with the assessment and correction of RNA degradation effects in Affymetrix 3' expression arrays. The parameter d gives a robust and accurate measure of RNA integrity. The correction removes the probe positional bias, and thus improves comparability of samples that are affected by RNA degradation.

Author: Mario Fasold

Maintainer: Mario Fasold <fasold at>

Citation (from within R, enter citation("AffyRNADegradation")):


To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

AffyRNADegradation Example PDF R Script
Reference Manual PDF


biocViews GeneExpression, Microarray, OneChannel, Preprocessing, QualityControl, Software
Version 1.48.0
In Bioconductor since BioC 2.10 (R-2.15) (12 years)
License GPL-2
Depends R (>= 2.9.0), methods, affy
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Suggests AmpAffyExample, hgu133acdf
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Follow Installation instructions to use this package in your R session.

Source Package AffyRNADegradation_1.48.0.tar.gz
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macOS Binary (x86_64) AffyRNADegradation_1.48.0.tgz
macOS Binary (arm64) AffyRNADegradation_1.48.0.tgz
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Source Repository (Developer Access) git clone
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