DOI: 10.18129/B9.bioc.ACE    

Absolute Copy Number Estimation from Low-coverage Whole Genome Sequencing

Bioconductor version: Release (3.8)

Uses segmented copy number data to estimate tumor cell percentage and produce copy number plots displaying absolute copy numbers.

Author: Jos B Poell

Maintainer: Jos B Poell <j.poell at>

Citation (from within R, enter citation("ACE")):


To install this package, start R (version "3.5") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
BiocManager::install("ACE", version = "3.8")

For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



HTML R Script ACE vignette
PDF   Reference Manual
Text   NEWS


biocViews CopyNumberVariation, Coverage, DNASeq, Sequencing, Software, Visualization, WholeGenome
Version 1.0.0
In Bioconductor since BioC 3.8 (R-3.5) (< 6 months)
License GPL-2
Depends R (>= 3.4)
Imports Biobase, QDNAseq, ggplot2, grid, stats, utils, methods, grDevices
Suggests knitr, rmarkdown, BiocStyle
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package ACE_1.0.0.tar.gz
Windows Binary
Mac OS X 10.11 (El Capitan) ACE_1.0.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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