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prolfqua

This is the development version of prolfqua; to use it, please install the devel version of Bioconductor.

Proteomics Label Free Quantification


Bioconductor version: Development (3.24)

The prolfqua package integrates essential steps of the mass spectrometry based label free quantification data analysis workflow: quality control, data normalization, protein aggregation, modeling, hypothesis testing and sample size estimation. We use prolfqua to : develop highly customizable, visually appealing, and interactive data analysis reports in pdf or HTML format; to visualize and model simple experimental designs with a single explanatory variable and complex experiments with multiple factors; to benchmark data acquisition, data preprocessing or data modeling methods. We developed and improved the package by applying the "Eating your own dog food" principle, when analysing dozens of proteomics datasets.

Author: Witold Wolski [aut] ORCID iD ORCID: 0000-0002-6468-120X , Functional Genomics Center Zurich [fnd], Christian Panse [cre] ORCID iD ORCID: 0000-0003-1975-3064

Maintainer: Christian Panse <cp at fgcz.ethz.ch>

Citation (from within R, enter citation("prolfqua")):

Witold Wolski. prolfqua: Proteomics Label Free Quantification. doi:10.18129/B9.bioc.prolfqua, R package version 0.99.2, https://bioconductor.org/packages/prolfqua.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("prolfqua")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("prolfqua")
Comparing Two Groups with prolfqua HTML R Script
Introduction to prolfqua HTML R Script
Reference ManualPDF

Details

biocViews MassSpectrometry, Metabolomics, Normalization, Preprocessing, Proteomics, QualityControl, Software
Version0.99.2
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5)
Imports circlize, ComplexHeatmap, dplyr, forcats, ggplot2, ggbeeswarm, ggrepel, limma, lme4, lmerTest, logistf, MASS, methods, plotly, progress, purrr, rlang, stringi, tidyselect, tidyr, tibble, UpSetR, withr
System Requirements
URLhttps://github.com/fgcz/prolfqua https://fgcz.github.io/prolfqua/
Bug Reportshttps://github.com/fgcz/prolfqua/issues
See More
Suggests BiocCheck, BiocStyle, corrplot, covr, crosstalk, cyclocomp, devtools, goodpractice, gridExtra, KernSmooth, knitr, limpa, lintr, pkgdown, preprocessCore, rcmdcheck, Rfit, rmarkdown, roxygen2, S4Vectors, SummarizedExperiment, testthat, vsn
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package prolfqua_0.99.2.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) prolfqua_0.99.2.tgz
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/prolfqua
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/prolfqua
Package Short Url https://bioconductor.org/packages/prolfqua/
Package Downloads ReportDownload Stats