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pfamAnalyzeR

This is the released version of pfamAnalyzeR; for the devel version, see pfamAnalyzeR.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17

Identification of domain isotypes in pfam data


Bioconductor version: Release (3.23)

Protein domains is one of the most import annoation of proteins we have with the Pfam database/tool being (by far) the most used tool. This R package enables the user to read the pfam prediction from both webserver and stand-alone runs into R. We have recently shown most human protein domains exist as multiple distinct variants termed domain isotypes. Different domain isotypes are used in a cell, tissue, and disease-specific manner. Accordingly, we find that domain isotypes, compared to each other, modulate, or abolish the functionality of a protein domain. This R package enables the identification and classification of such domain isotypes from Pfam data.

Author: Kristoffer Vitting-Seerup [cre, aut] ORCID iD ORCID: 0000-0002-6450-0608

Maintainer: Kristoffer Vitting-Seerup <k.vitting.seerup at gmail.com>

Citation (from within R, enter citation("pfamAnalyzeR")):

Kristoffer Vitting-Seerup. pfamAnalyzeR: Identification of domain isotypes in pfam data. doi:10.18129/B9.bioc.pfamAnalyzeR, R package version 1.12.0, https://bioconductor.org/packages/pfamAnalyzeR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("pfamAnalyzeR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("pfamAnalyzeR")
pfamAnalyzeR HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews AlternativeSplicing, Annotation, BiomedicalInformatics, DataImport, FunctionalGenomics, FunctionalPrediction, GenePrediction, Software, SystemsBiology, TranscriptomeVariant
Version1.12.0
In Bioconductor sinceBioC 3.17 (R-4.3) (3.5 years)
License MIT + file LICENSE
Depends R (>= 4.3.0), readr, stringr, dplyr
Imports utils, tibble, magrittr
System Requirements
URL
Bug Reportshttps://github.com/kvittingseerup/pfamAnalyzeR/issues
See More
Suggests BiocStyle, knitr, rmarkdown
Linking To
Enhances
Depends On Me IsoformSwitchAnalyzeR
Imports Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package pfamAnalyzeR_1.12.0.tar.gz
Windows Binary (x86_64) pfamAnalyzeR_1.12.0.zip
macOS Binary (big-sur-x86_64) pfamAnalyzeR_1.12.0.tgz
macOS Binary (sonoma-arm64) pfamAnalyzeR_1.12.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/pfamAnalyzeR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/pfamAnalyzeR
Package Short Url https://bioconductor.org/packages/pfamAnalyzeR/
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