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normScore

This is the development version of normScore; to use it, please install the devel version of Bioconductor.

Evaluation and Ranking of Normalization Methods for Proteomics Data


Bioconductor version: Development (3.24)

Provides tools to evaluate and rank normalization methods for omics datasets using a composite score derived from multiple performance metrics. The package is designed to support systematic benchmarking and comparison of normalization strategies across datasets and experimental settings. It also includes utilities for summarizing results and visualizing normalization performance.

Author: Julia García Currás [aut, cre] ORCID iD ORCID: 0009-0002-6354-5035 , Axencia Galega de Innovación (GAIN), Xunta de Galicia [fnd] (Industrial Doctorate Grant 2022-2026, Ref. 23_IN606D_2022_2707220)

Maintainer: Julia García Currás <julia.gcurras at udc.es>

Citation (from within R, enter citation("normScore")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("normScore")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("normScore")
Getting started with normScore HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews MultipleComparison, Normalization, Preprocessing, Proteomics, QualityControl, Software
Version 0.99.1
In Bioconductor since BioC 3.24 (R-4.6)
License GPL-2
Depends R (>= 4.6)
Imports stats, ggplot2, ggpubr, boot, MASS, rlang, withr
System Requirements
URL https://github.com/juliagcurras/normScore https://juliagcurras.github.io/normScore/
Bug Reports https://https://github.com/juliagcurras/normScore/issues
See More
Suggests knitr, rmarkdown, testthat (>= 3.0.0), limma, NormalyzerDE, SummarizedExperiment, S4Vectors, methods, BiocStyle, BiocManager
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package normScore_0.99.1.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) normScore_0.99.1.tgz
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/normScore
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/normScore
Bioc Package Browser https://code.bioconductor.org/browse/normScore/
Package Short Url https://bioconductor.org/packages/normScore/
Package Downloads Report Download Stats