Bioconductor Developer Survey 2026 Now Open!

msmsTests

This is the released version of msmsTests; for the devel version, see msmsTests.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14, 2.13

LC-MS/MS Differential Expression Tests


Bioconductor version: Release (3.23)

Statistical tests for label-free LC-MS/MS data by spectral counts, to discover differentially expressed proteins between two biological conditions. Three tests are available: Poisson GLM regression, quasi-likelihood GLM regression, and the negative binomial of the edgeR package.The three models admit blocking factors to control for nuissance variables.To assure a good level of reproducibility a post-test filter is available, where we may set the minimum effect size considered biologicaly relevant, and the minimum expression of the most abundant condition.

Author: Josep Gregori, Alex Sanchez, and Josep Villanueva

Maintainer: Josep Gregori i Font <josep.gregori at gmail.com>

Citation (from within R, enter citation("msmsTests")):

Josep Gregori, Alex Sanchez, and Josep Villanueva. msmsTests: LC-MS/MS Differential Expression Tests. doi:10.18129/B9.bioc.msmsTests, R package version 1.50.0, https://bioconductor.org/packages/msmsTests.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("msmsTests")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("msmsTests")
msmsTests: post test filters to improve reproducibility PDF R Script
msmsTests: controlling batch effects by blocking PDF R Script
Reference ManualPDF

Details

biocViews ImmunoOncology, MassSpectrometry, Proteomics, Software
Version1.50.0
In Bioconductor sinceBioC 2.13 (R-3.0) (13 years)
License GPL-2
Depends R (>= 3.0.1), MSnbase, msmsEDA
Imports edgeR, qvalue
System Requirements
URL
See More
Suggests xtable
Linking To
Enhances
Depends On Me
Imports Me MSnID
Suggests Me RforProteomics
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package msmsTests_1.50.0.tar.gz
Windows Binary (x86_64) msmsTests_1.50.0.zip
macOS Binary (big-sur-x86_64) msmsTests_1.50.0.tgz
macOS Binary (sonoma-arm64) msmsTests_1.50.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/msmsTests
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/msmsTests
Package Short Url https://bioconductor.org/packages/msmsTests/
Package Downloads ReportDownload Stats