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gscreend

This is the released version of gscreend; for the devel version, see gscreend.

All Bioconductor versions of gscreend

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10

Analysis of pooled genetic screens

Bioconductor version: 3.23 · Package version: 1.26.0

Package for the analysis of pooled genetic screens (e.g. CRISPR-KO). The analysis of such screens is based on the comparison of gRNA abundances before and after a cell proliferation phase. The gscreend packages takes gRNA counts as input and allows detection of genes whose knockout decreases or increases cell proliferation.

Author: Katharina Imkeller [cre, aut], Wolfgang Huber [aut]

Maintainer: Katharina Imkeller <k.imkeller at dkfz.de>

DOI: 10.18129/B9.bioc.gscreend

Citation

From within R, enter citation("gscreend"):

Katharina Imkeller, Wolfgang Huber. gscreend: Analysis of pooled genetic screens. doi:10.18129/B9.bioc.gscreend, R package version 1.26.0, https://bioconductor.org/packages/gscreend.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("gscreend")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.26.0
LicenseGPL-3
URLhttps://github.com/imkeller/gscreend
Bug Reportshttps://github.com/imkeller/gscreend/issues
Last updated2026-04-28
In Bioconductor sinceBioC 3.10 (R-3.6) (6 years)
Downloads rank1399 of 2,418
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsCRISPR, PooledScreens, Software, StatisticalMethod
Package Short Url https://bioconductor.org/packages/gscreend/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("gscreend")
Vignette illustrating the usage of gscreend on simulated data HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagegscreend_1.26.0.tar.gz
Windows binary (x86_64)gscreend_1.26.0.zip
macOS binary (arm64)gscreend_1.26.0.tgz
macOS binary (x86_64)gscreend_1.26.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/gscreend
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/gscreend
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 3.6)

Imports: SummarizedExperiment, nloptr, fGarch, methods, BiocParallel, graphics

Suggests: knitr, testthat, rmarkdown, BiocStyle